Burkholderia cenocepacia K56-2, WQ49_RS04255 (paaK2)
Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
Gene Feature Overview
| Strain |
Burkholderia cenocepacia K56-2
GCF_000981305.1|latest |
| Locus Tag |
WQ49_RS04255
|
| NCBI Old Locus Tag | WQ49_04260 |
| Name |
paaK2
|
| Replicon | scf7180000000049 |
| Genomic location | 366639 - 367961 (- strand) |
Cross-References
| RefSeq | WP_006483970.1 |
| GI | 493529955 |
| NCBI Locus Tag | WQ49_RS04255 |
| NCBI Old Locus Tag | WQ49_04260 |
| RefSeq | WP_006483970.1 |
Product
| Feature Type | CDS |
| Coding Frame | 1 |
| Product Name |
Paak2
|
| Synonyms |
phenylacetate-CoA ligase |
| Evidence for Translation | |
| Charge (pH 7) | -4.43 |
| Kyte-Doolittle Hydrophobicity Value | -0.147 |
| Molecular Weight (kDa) | 48042.4 |
| Isoelectric Point (pI) | 6.30 |
Subcellular localization
| Individual Mappings | |
| Additional evidence for subcellular localization |
PDB 3D Structures
| Accession | Header | Accession Date | Compound | Source | Resolution | Method | Percent Identity |
| 2Y4O | LIGASE | 01/07/11 | Crystal Structure of PaaK2 in complex with phenylacetyl adenylate | BURKHOLDERIA CENOCEPACIA | 1.9 | X-RAY DIFFRACTION | 100.0 |
Orthologs/Comparative Genomics
| Burkholderia Ortholog Group |
BG003587 (315 members) |
| Putative Inparalogs | None Found |
Interactions
| STRING database | Search for predicted protein-protein interactions using:
Search term: WQ49_RS04255
Search term: paaK2
Search term: Paak2
|
Human Homologs
References
|
Defining a structural and kinetic rationale for paralogous copies of phenylacetate-CoA ligases from the cystic fibrosis pathogen Burkholderia cenocepacia J2315.
Law A, Boulanger MJ
J Biol Chem 2011 Apr 29;286(17):15577-85
PubMed ID: 21388965
|