Burkholderia cenocepacia J2315, BCAL1611 (pyrD)

Gene Feature Overview

Strain	Burkholderia cenocepacia J2315 GCF_000009485.1|latest
Locus Tag	BCAL1611
NCBI Locus Tag	QU43_RS44565
Name	pyrD
Replicon	chromosome 1
Genomic location	1768636 - 1769673 (- strand)

Cross-References

RefSeq	WP_012492588.1
GI	206559975
Entrez	6931882
GI	206559975
INSDC	CAR51909.1
NCBI Locus Tag	QU43_RS44565
NCBI Old Locus Tag	BCAL1611
RefSeq	WP_012492588.1,GeneID
UniParc	UPI00017B9593
UniProtKB Acc	B4E8N4
UniProtKB ID	PYRD_BURCJ
UniRef100	UniRef100_B4E8N4
UniRef50	UniRef50_Q2Y5H8
UniRef90	UniRef90_Q1BWM4

Product

Feature Type	CDS
Coding Frame	1
Product Name	dihydroorotate dehydrogenase 2
Synonyms
Evidence for Translation
Charge (pH 7)	4.59
Kyte-Doolittle Hydrophobicity Value	-0.021
Molecular Weight (kDa)	36788.8
Isoelectric Point (pI)	8.77

Subcellular localization

Individual Mappings	Localization Confidence PMID Cytoplasmic Membrane Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 588 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group	BG001381 (654 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: BCAL1611 Search term: pyrD Search term: dihydroorotate dehydrogenase 2

Human Homologs

Ensembl 97, assembly GRCh38.p12

ENSP00000219240 dihydroorotate dehydrogenase (quinone) [Source:HGNC Symbol;Acc:HGNC:2867] E-value: 5.0e-68 Percent Identity: 45.0

References