Burkholderia cenocepacia J2315, BCAL1611 (pyrD)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Cellular Component GO:0005737 cytoplasm
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF01180
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006207 'de novo' pyrimidine nucleobase biosynthetic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PS00912
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF01180
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003824 catalytic activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:G3DSA:3.20.20.70
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006222 UMP biosynthetic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PIRSF000164
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0055114 oxidation-reduction process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PIRSF000164
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0004152 dihydroorotate dehydrogenase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PIRSF000164
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Cellular Component GO:0016020 membrane
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01036
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Pathways

Database Xref Pathway Version Evidence PMID
MetaCyc UMP biosynthesis I InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG bcj00240 Pyrimidine metabolism 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG bcj01100 Metabolic pathways 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG (InterPro) 00240 Pyrimidine metabolism InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
SUPERFAMILY SSF51395 6 339 3.55E-105
Coils Coil 193 213 -
ProSitePatterns PS00911 Dihydroorotate dehydrogenase signature 1. IPR001295 Dihydroorotate dehydrogenase, conserved site 83 102 -
CDD cd04738 DHOD_2_like IPR005719 Dihydroorotate dehydrogenase, class 2 10 339 3.71246E-178
TIGRFAM TIGR01036 pyrD_sub2: dihydroorotate dehydrogenase (fumarate) IPR005719 Dihydroorotate dehydrogenase, class 2 6 341 6.0E-133
Pfam PF01180 Dihydroorotate dehydrogenase IPR005720 Dihydroorotate dehydrogenase domain 51 340 7.5E-90
Hamap MF_00225 Dihydroorotate dehydrogenase (quinone) [pyrD]. IPR005719 Dihydroorotate dehydrogenase, class 2 5 339 51.818
PIRSF PIRSF000164 IPR012135 Dihydroorotate dehydrogenase, class 1/ 2 15 344 1.9E-97
ProSitePatterns PS00912 Dihydroorotate dehydrogenase signature 2. IPR001295 Dihydroorotate dehydrogenase, conserved site 295 315 -
Gene3D G3DSA:3.20.20.70 IPR013785 Aldolase-type TIM barrel 5 339 1.5E-135

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.