Burkholderia cenocepacia J2315, BCAM2232 (pchD)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Burkholderia cenocepacia J2315
GCF_000009485.1|latest
Locus Tag
BCAM2232
NCBI Locus TagQU43_RS65525
Name
pchD
Replicon chromosome 2
Genomic location 2502352 - 2504001 (+ strand)

Cross-References

RefSeq WP_012493510.1
GI 206564067
Entrez 6930593
GI 206564067
INSDC CAR56089.1
NCBI Locus Tag QU43_RS65525
NCBI Old Locus Tag BCAM2232
RefSeq WP_012493510.1,GeneID
UniParc UPI00017BA020
UniProtKB Acc B4EGG3
UniProtKB ID B4EGG3_BURCJ
UniRef100 UniRef100_A0A0D1C976
UniRef50 UniRef50_Q0S7A8
UniRef90 UniRef90_G7HSM8

Product

Feature Type CDS
Coding Frame 1
Product Name
putative pyochelin biosynthetic protein PchD
Synonyms
Evidence for Translation
Charge (pH 7) -2.34
Kyte-Doolittle Hydrophobicity Value -0.053
Molecular Weight (kDa) 59537.2
Isoelectric Point (pI) 6.69

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 593 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG001594 (514 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BCAM2232
Search term: pchD

Human Homologs

Ensembl 97, assembly GRCh38.p12
acyl-CoA synthetase short chain family member 1 [Source:HGNC Symbol;Acc:HGNC:16091]
E-value: 3.7e-20
Percent Identity: 23.3

References

Dihydroaeruginoic acid synthetase and pyochelin synthetase, products of the pchEF genes, are induced by extracellular pyochelin in Pseudomonas aeruginosa.
Reimmann C, Serino L, Beyeler M, Haas D
Microbiology 1998 Nov;144 ( Pt 11):3135-48
PubMed ID: 9846750
Erratum in: J Bacteriol. 2009 Apr;191(8):2907.
The genome of Burkholderia cenocepacia J2315, an epidemic pathogen of cystic fibrosis patients.
J Bacteriol. 2009 Jan;191(1):261-77.
PubMed ID: 18931103