Burkholderia cenocepacia J2315, BCAL2021

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia cenocepacia J2315
GCF_000009485.1|latest
Locus Tag
BCAL2021
NCBI Locus TagQU43_RS46665
Name
Replicon chromosome 1
Genomic location 2230412 - 2232934 (- strand)

Cross-References

RefSeq WP_006488026.1
GI 206560384
Entrez 6932190
GI 206560384
INSDC CAR52321.1
NCBI Locus Tag QU43_RS46665
NCBI Old Locus Tag BCAL2021
RefSeq WP_006488026.1,GeneID
UniParc UPI00017B95BC
UniProtKB Acc B4EC28
UniProtKB ID B4EC28_BURCJ
UniRef100 UniRef100_G7HE67
UniRef50 UniRef50_Q7NZT7
UniRef90 UniRef90_Q39FB3

Product

Feature Type CDS
Coding Frame 1
Product Name
putative penicillin-binding protein
Product Name Confidence: Class 1
Synonyms Class A penicillin-binding protein
Evidence for Translation
Charge (pH 7) 2.43
Kyte-Doolittle Hydrophobicity Value -0.288
Molecular Weight (kDa) 91369.9
Isoelectric Point (pI) 7.86

Subcellular localization

Individual Mappings
Localization Confidence PMID
Extracellular Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 563 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG000296 (1307 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BCAL2021

Human Homologs

References

Expression and characterization of penicillin-binding proteins in Burkholderia cenocepacia.
Specht KM, Sheetz KH, Alexander CM, Lamech LT, O'Connor LH, Walker DM, Stevenson HP
Curr Microbiol 2010 Apr;60(4):274-9
PubMed ID: 19924480