Burkholderia cenocepacia J2315, BCAL2021

Gene Feature Overview

Strain	Burkholderia cenocepacia J2315 GCF_000009485.1|latest
Locus Tag	BCAL2021
NCBI Locus Tag	QU43_RS46665
Name
Replicon	chromosome 1
Genomic location	2230412 - 2232934 (- strand)

Cross-References

RefSeq	WP_006488026.1
GI	206560384
Entrez	6932190
GI	206560384
INSDC	CAR52321.1
NCBI Locus Tag	QU43_RS46665
NCBI Old Locus Tag	BCAL2021
RefSeq	WP_006488026.1,GeneID
UniParc	UPI00017B95BC
UniProtKB Acc	B4EC28
UniProtKB ID	B4EC28_BURCJ
UniRef100	UniRef100_G7HE67
UniRef50	UniRef50_Q7NZT7
UniRef90	UniRef90_Q39FB3

Product

Feature Type	CDS
Coding Frame	1
Product Name	putative penicillin-binding protein Product Name Confidence: Class 1
Synonyms	Class A penicillin-binding protein
Evidence for Translation
Charge (pH 7)	2.43
Kyte-Doolittle Hydrophobicity Value	-0.288
Molecular Weight (kDa)	91369.9
Isoelectric Point (pI)	7.86

Subcellular localization

Individual Mappings	Localization Confidence PMID Extracellular Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 563 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group	BG000296 (1307 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: BCAL2021 Search term: putative penicillin-binding protein

Human Homologs

References

Expression and characterization of penicillin-binding proteins in Burkholderia cenocepacia. Specht KM, Sheetz KH, Alexander CM, Lamech LT, O'Connor LH, Walker DM, Stevenson HP Curr Microbiol 2010 Apr;60(4):274-9 PubMed ID: 19924480