Burkholderia cenocepacia MC0-3, Bcenmc03_3710 (ecfL)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Feature Overview

Strain Burkholderia cenocepacia MC0-3
GCF_000019505.1|latest
Locus Tag
Bcenmc03_3710
NCBI Locus TagBCENMC03_RS18765
Name
ecfL
Replicon chromosome 2
Genomic location 617399 - 618667 (- strand)

Cross-References

RefSeq WP_011548203.1
GI 170736092
Entrez 6126544
GI 170736092
INSDC ACA92862.1
NCBI Locus Tag BCENMC03_RS18765
NCBI Old Locus Tag Bcenmc03_3710
RefSeq WP_011548203.1
UniParc UPI00006DA4AF
UniProtKB Acc B1K4E4
UniProtKB ID B1K4E4_BURCC
UniRef100 UniRef100_A0AYS5
UniRef50 UniRef50_C5CSL3
UniRef90 UniRef90_A4JLM3

Product

Feature Type CDS
Coding Frame 1
Product Name
RNA polymerase ECF-subfamily sigma factor
Product Name Confidence: Class 1
Synonyms sigma factor 70 EcfL
Evidence for Translation
Charge (pH 7) -7.18
Kyte-Doolittle Hydrophobicity Value 0.010
Molecular Weight (kDa) 45911.1
Isoelectric Point (pI) 5.96

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 146 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG004844 (654 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: Bcenmc03_3710
Search term: ecfL

Human Homologs

References

Architecture of Burkholderia cepacia complex sigma70 gene family: evidence of alternative primary and clade-specific factors, and genomic instability.
Menard A, de Los Santos PE, Graindorge A, Cournoyer B
BMC Genomics 2007 Sep 4;8:308
PubMed ID: 17784948