Burkholderia pseudomallei K96243, BPSL2239 (ask)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest
Locus Tag
BPSL2239
Name
ask
Replicon chromosome 1
Genomic location 2700393 - 2701643 (- strand)

Cross-References

RefSeq YP_108834.1
GI 53719848
Entrez 3094028
GI 53719848
INSDC CAH36241.1
NCBI Locus Tag BPSL2239
RefSeq YP_108834.1,GeneID
UniParc UPI000043B2E1
UniProtKB Acc Q63ST2
UniProtKB ID Q63ST2_BURPS
UniRef100 UniRef100_A0A069B901
UniRef50 UniRef50_Q1LPF1
UniRef90 UniRef90_Q13X64

Product

Feature Type CDS
Coding Frame 1
Product Name
aspartate kinase
Synonyms
Evidence for Translation
Charge (pH 7) -14.08
Kyte-Doolittle Hydrophobicity Value -0.067
Molecular Weight (kDa) 45141.2
Isoelectric Point (pI) 4.81

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Extracellular Class 1
quantitative mass spectrometry evidence
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 639 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG001966 (653 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSL2239
Search term: ask
Search term: aspartate kinase

References

Quantitative proteomic analysis of Burkholderia pseudomallei Bsa type III secretion system effectors using hypersecreting mutants.
Vander Broek CW, Chalmers KJ, Stevens MP, Stevens JM
Mol Cell Proteomics 2015 Apr;14(4):905-16
PubMed ID: 25635268