Burkholderia pseudomallei K96243, BPSL2239 (ask)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0009089 lysine biosynthetic process via diaminopimelate
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PIRSF000726
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0004072 aspartate kinase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PIRSF000726
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0008652 cellular amino acid biosynthetic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00657
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Pathways

Database Xref Pathway Version Evidence PMID
KEGG bps01230 Biosynthesis of amino acids 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
MetaCyc spermidine biosynthesis II InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
MetaCyc L-lysine biosynthesis VI InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG (InterPro) 00270 Cysteine and methionine metabolism InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG bps00260 Glycine, serine and threonine metabolism 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
MetaCyc grixazone biosynthesis InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG bps01210 2-Oxocarboxylic acid metabolism 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
MetaCyc L-lysine biosynthesis II InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG (InterPro) 00260 Glycine, serine and threonine metabolism InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG bps01110 Biosynthesis of secondary metabolites 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
MetaCyc L-methionine biosynthesis IV (archaea) InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
MetaCyc norspermidine biosynthesis InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
MetaCyc 3-dehydroquinate biosynthesis II (archaea) InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
MetaCyc L-lysine biosynthesis III InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG bps01120 Microbial metabolism in diverse environments 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG (InterPro) 00261 Monobactam biosynthesis InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG bps01130 Biosynthesis of antibiotics 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG bps00270 Cysteine and methionine metabolism 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG (InterPro) 00300 Lysine biosynthesis InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG bps01100 Metabolic pathways 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG bps00300 Lysine biosynthesis 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Gene3D G3DSA:3.30.70.260 263 413 3.6E-57
CDD cd04261 AAK_AKii-LysC-BS IPR041740 Aspartokinase catalytic domain 3 250 3.43997E-135
ProSitePatterns PS00324 Aspartokinase signature. IPR018042 Aspartate kinase, conserved site 5 13 -
CDD cd04913 ACT_AKii-LysC-BS-like_1 271 346 4.84088E-28
Pfam PF13840 ACT domain IPR027795 CASTOR, ACT domain 349 409 6.2E-17
SUPERFAMILY SSF55021 342 414 8.51E-25
PIRSF PIRSF000726 IPR005260 Aspartate kinase, monofunctional class 57 416 2.6E-142
SUPERFAMILY SSF53633 IPR036393 Acetylglutamate kinase-like superfamily 4 250 1.44E-73
Gene3D G3DSA:3.30.70.260 270 348 3.6E-57
Gene3D G3DSA:3.40.1160.10 IPR036393 Acetylglutamate kinase-like superfamily 1 262 1.5E-86
ProSiteProfiles PS51671 ACT domain profile. IPR002912 ACT domain 355 416 12.727
Pfam PF01842 ACT domain IPR002912 ACT domain 277 331 7.3E-10
TIGRFAM TIGR00656 asp_kin_monofn: aspartate kinase, monofunctional class IPR005260 Aspartate kinase, monofunctional class 1 413 1.0E-127
SUPERFAMILY SSF55021 257 335 5.89E-18
PRINTS PR00474 Glutamate 5-kinase family signature IPR001057 Glutamate/acetylglutamate kinase 152 179 8.1E-5
Pfam PF00696 Amino acid kinase family IPR001048 Aspartate/glutamate/uridylate kinase 3 229 4.6E-50
PRINTS PR00474 Glutamate 5-kinase family signature IPR001057 Glutamate/acetylglutamate kinase 33 47 8.1E-5
TIGRFAM TIGR00657 asp_kinases: aspartate kinase IPR001341 Aspartate kinase 63 412 2.5E-113
ProSiteProfiles PS51671 ACT domain profile. IPR002912 ACT domain 274 349 11.373
PIRSF PIRSF000726 IPR005260 Aspartate kinase, monofunctional class 1 61 1.7E-23
CDD cd04923 ACT_AK-LysC-DapG-like_2 360 413 2.5927E-27

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.