Burkholderia pseudomallei K96243, BPSL2148 (fabZ)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest
Locus Tag
BPSL2148
Name
fabZ
Replicon chromosome 1
Genomic location 2577935 - 2578444 (- strand)

Cross-References

RefSeq YP_108743.1
GI 53719757
Entrez 3094303
GI 53719757
INSDC CAH36150.1
NCBI Locus Tag BPSL2148
RefSeq YP_108743.1,GeneID
UniParc UPI0000440D14
UniProtKB Acc Q63T23
UniProtKB ID FABZ_BURPS
UniRef100 UniRef100_A3MKT1
UniRef50 UniRef50_A1WX12
UniRef90 UniRef90_Q0BE26

Product

Feature Type CDS
Coding Frame 1
Product Name
(3R)-hydroxymyristoyl-ACP dehydratase
Synonyms
Evidence for Translation
Charge (pH 7) 4.13
Kyte-Doolittle Hydrophobicity Value 0.005
Molecular Weight (kDa) 19052.1
Isoelectric Point (pI) 9.12

Subcellular localization

Individual Mappings
Localization Confidence PMID
Extracellular Class 1
quantitative mass spectrometry evidence
Cytoplasmic Class 3
Additional evidence for subcellular localization

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
4H4G LYASE 09/17/12 Crystal Structure of (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase from Burkholderia thailandensis E264 BURKHOLDERIA THAILANDENSIS 2.65 X-RAY DIFFRACTION 98.1

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 506 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG001898 (654 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSL2148
Search term: fabZ

References

Quantitative proteomic analysis of Burkholderia pseudomallei Bsa type III secretion system effectors using hypersecreting mutants.
Vander Broek CW, Chalmers KJ, Stevens MP, Stevens JM
Mol Cell Proteomics 2015 Apr;14(4):905-16
PubMed ID: 25635268