Burkholderia pseudomallei K96243, BPSL2148 (fabZ)
Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
Gene Ontology
| Ontology | Accession | Term | GO Evidence | Evidence Ontology (ECO) Code | Reference | Comments |
|---|---|---|---|---|---|---|
| Molecular Function | GO:0016836 | hydro-lyase activity |
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01750
|
ECO:0000259 match to InterPro signature evidence used in automatic assertion |
||
| Biological Process | GO:0006633 | fatty acid biosynthetic process |
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01750
|
ECO:0000259 match to InterPro signature evidence used in automatic assertion |
||
| Molecular Function | GO:0016836 | hydro-lyase activity |
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01750
|
ECO:0000259 match to InterPro signature evidence used in automatic assertion |
||
| Biological Process | GO:0006633 | fatty acid biosynthetic process |
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01750
|
ECO:0000259 match to InterPro signature evidence used in automatic assertion |
Pathways
| Database | Xref | Pathway | Version | Evidence | PMID |
|---|---|---|---|---|---|
| MetaCyc | 8-amino-7-oxononanoate biosynthesis I | InterPro 5.36-75.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
||
| MetaCyc | gondoate biosynthesis (anaerobic) | InterPro 5.36-75.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
||
| MetaCyc | <i>cis</i>-vaccenate biosynthesis | InterPro 5.36-75.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
||
| MetaCyc | oleate biosynthesis IV (anaerobic) | InterPro 5.36-75.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
||
| MetaCyc | stearate biosynthesis II (bacteria and plants) | InterPro 5.36-75.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
||
| KEGG (InterPro) | 00061 | Fatty acid biosynthesis | InterPro 5.36-75.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
|
| KEGG | bps00061 | Fatty acid biosynthesis | 73.0+/03-31, Mar 15 |
ECO:0000249
sequence similarity evidence used in automatic assertion |
|
| MetaCyc | superpathway of mycolate biosynthesis | InterPro 5.36-75.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
||
| MetaCyc | (5Z)-dodecenoate biosynthesis II | InterPro 5.36-75.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
||
| KEGG | bps00780 | Biotin metabolism | 73.0+/03-31, Mar 15 |
ECO:0000249
sequence similarity evidence used in automatic assertion |
|
| MetaCyc | palmitate biosynthesis II (bacteria and plants) | InterPro 5.36-75.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
||
| MetaCyc | mycolate biosynthesis | InterPro 5.36-75.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
||
| KEGG | bps01212 | Fatty acid metabolism | 73.0+/03-31, Mar 15 |
ECO:0000249
sequence similarity evidence used in automatic assertion |
|
| KEGG (InterPro) | 00780 | Biotin metabolism | InterPro 5.36-75.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
|
| KEGG | bps01100 | Metabolic pathways | 73.0+/03-31, Mar 15 |
ECO:0000249
sequence similarity evidence used in automatic assertion |
|
| MetaCyc | palmitate biosynthesis I (animals and fungi) | InterPro 5.36-75.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
||
| MetaCyc | octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast) | InterPro 5.36-75.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
||
| MetaCyc | palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate) | InterPro 5.36-75.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
Functional Predictions from Interpro
| Analysis | Accession | Description | Interpro Accession | Interpro Description | Amino Acid Start | Amino Acid Stop | E-value |
|---|---|---|---|---|---|---|---|
| TIGRFAM | TIGR01750 | fabZ: beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ | IPR010084 | Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ | 22 | 161 | 1.4E-60 |
| Gene3D | G3DSA:3.10.129.10 | 10 | 169 | 4.6E-62 | |||
| SUPERFAMILY | SSF54637 | IPR029069 | HotDog domain superfamily | 24 | 164 | 1.64E-47 | |
| CDD | cd01288 | FabZ | 31 | 163 | 6.93211E-67 | ||
| Pfam | PF07977 | FabA-like domain | IPR013114 | Beta-hydroxydecanoyl thiol ester dehydrase, FabA/FabZ | 31 | 157 | 5.9E-37 |
| Hamap | MF_00406 | 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ [fabZ]. | IPR010084 | Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ | 22 | 164 | 35.875 |
Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.