Burkholderia pseudomallei K96243, BPSL2009 (alaS)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest
Locus Tag
BPSL2009
Name
alaS
Replicon chromosome 1
Genomic location 2395633 - 2398257 (- strand)

Cross-References

RefSeq YP_108607.1
GI 53719621
Entrez 3094503
GI 53719621
INSDC CAH36008.1
NCBI Locus Tag BPSL2009
RefSeq YP_108607.1,GeneID
UniParc UPI000043B200
UniProtKB Acc Q63TF9
UniProtKB ID SYA_BURPS
UniRef100 UniRef100_A3MJ36
UniRef50 UniRef50_Q39HB7
UniRef90 UniRef90_A0K6N4

Product

Feature Type CDS
Coding Frame 1
Product Name
alanyl-tRNA synthetase
Synonyms
Evidence for Translation
Charge (pH 7) -12.86
Kyte-Doolittle Hydrophobicity Value -0.231
Molecular Weight (kDa) 94694.4
Isoelectric Point (pI) 6.14

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Extracellular Class 1
quantitative mass spectrometry evidence
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 667 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG001236 (654 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSL2009
Search term: alaS

Human Homologs

Ensembl 97, assembly GRCh38.p12
alanyl-tRNA synthetase [Source:HGNC Symbol;Acc:HGNC:20]
E-value: 2.3e-125
Percent Identity: 36.3

References

Quantitative proteomic analysis of Burkholderia pseudomallei Bsa type III secretion system effectors using hypersecreting mutants.
Vander Broek CW, Chalmers KJ, Stevens MP, Stevens JM
Mol Cell Proteomics 2015 Apr;14(4):905-16
PubMed ID: 25635268