Burkholderia pseudomallei K96243, BPSL0998 (metG)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest
Locus Tag
BPSL0998
Name
metG
Replicon chromosome 1
Genomic location 1159815 - 1161992 (- strand)

Cross-References

RefSeq YP_107626.1
GI 53718640
Entrez 3091950
GI 53718640
INSDC CAH34994.1
NCBI Locus Tag BPSL0998
RefSeq YP_107626.1,GeneID
UniParc UPI000043AE30
UniProtKB Acc Q63W90
UniProtKB ID SYM_BURPS
UniRef100 UniRef100_A3NSL6
UniRef50 UniRef50_Q2T087
UniRef90 UniRef90_Q2T087

Product

Feature Type CDS
Coding Frame 1
Product Name
methionyl-tRNA synthetase
Synonyms
Evidence for Translation
Charge (pH 7) -4.88
Kyte-Doolittle Hydrophobicity Value -0.244
Molecular Weight (kDa) 79912.9
Isoelectric Point (pI) 6.52

Subcellular localization

Individual Mappings
Localization Confidence PMID
Extracellular Class 1
quantitative mass spectrometry evidence
Cytoplasmic Class 3
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 669 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG002308 (654 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSL0998
Search term: metG

Human Homologs

Ensembl 97, assembly GRCh38.p12
methionyl-tRNA synthetase 2, mitochondrial [Source:HGNC Symbol;Acc:HGNC:25133]
E-value: 7.9e-39
Percent Identity: 27.1

References

Quantitative proteomic analysis of Burkholderia pseudomallei Bsa type III secretion system effectors using hypersecreting mutants.
Vander Broek CW, Chalmers KJ, Stevens MP, Stevens JM
Mol Cell Proteomics 2015 Apr;14(4):905-16
PubMed ID: 25635268