Burkholderia cenocepacia K56-2, WQ49_RS11495 (paaF)
Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
Gene Feature Overview
| Strain |
Burkholderia cenocepacia K56-2
GCF_000981305.1|latest |
| Locus Tag |
WQ49_RS11495
|
| NCBI Old Locus Tag | WQ49_11500 |
| Name |
paaF
|
| Replicon | scf7180000000051 |
| Genomic location | 3442 - 4218 (- strand) |
Cross-References
| RefSeq | WP_006491102.1 |
| GI | 493537172 |
| NCBI Locus Tag | WQ49_RS11495 |
| NCBI Old Locus Tag | WQ49_11500 |
| RefSeq | WP_006491102.1 |
Product
| Feature Type | CDS |
| Coding Frame | 1 |
| Product Name |
PaaF
|
| Synonyms |
enoyl-CoA hydratase |
| Evidence for Translation | |
| Charge (pH 7) | -3.37 |
| Kyte-Doolittle Hydrophobicity Value | 0.074 |
| Molecular Weight (kDa) | 27995.1 |
| Isoelectric Point (pI) | 5.45 |
Subcellular localization
| Individual Mappings | |
| Additional evidence for subcellular localization |
AlphaFold 2 Protein Structure Predictions
Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.
Orthologs/Comparative Genomics
| Burkholderia Ortholog Group |
BG000434 (657 members) |
| Putative Inparalogs | None Found |
Interactions
| STRING database | Search for predicted protein-protein interactions using:
Search term: WQ49_RS11495
Search term: paaF
Search term: PaaF
|
Human Homologs
|
Ensembl
97, assembly
GRCh38.p12
|
enoyl-CoA hydratase, short chain 1 [Source:HGNC Symbol;Acc:HGNC:3151]
E-value:
4.6e-74
Percent Identity:
56.4
|
References
|
A functional phenylacetic acid catabolic pathway is required for full pathogenicity of Burkholderia cenocepacia in the Caenorhabditis elegans host model.
Law RJ, Hamlin JN, Sivro A, McCorrister SJ, Cardama GA, Cardona ST
J Bacteriol 2008 Nov;190(21):7209-18
PubMed ID: 18776009
|
|
Bacterial phenylalanine and phenylacetate catabolic pathway revealed.
Teufel R, Mascaraque V, Ismail W, Voss M, Perera J, Eisenreich W, Haehnel W, Fuchs G
Proc Natl Acad Sci U S A 2010 Aug 10;107(32):14390-5
PubMed ID: 20660314
|