Burkholderia cenocepacia J2315, BCAL2012

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia cenocepacia J2315
GCF_000009485.1|latest
Locus Tag
BCAL2012
NCBI Locus TagQU43_RS46620
Name
Replicon chromosome 1
Genomic location 2219712 - 2221073 (+ strand)

Cross-References

RefSeq WP_006488007.1
GI 206560375
Entrez 6933894
GI 206560375
INSDC CAR52312.1
NCBI Locus Tag QU43_RS46620
NCBI Old Locus Tag BCAL2012
RefSeq WP_006488007.1,GeneID
UniParc UPI00017B94F3
UniProtKB Acc B4EC19
UniProtKB ID B4EC19_BURCJ
UniRef100 UniRef100_B4EC19
UniRef50 UniRef50_A2VXK2
UniRef90 UniRef90_A2VXK2

Product

Feature Type CDS
Coding Frame 1
Product Name
putative oxidative stress related two-component regulatory system, sensor kinase protein
Synonyms
Evidence for Translation
Charge (pH 7) -3.01
Kyte-Doolittle Hydrophobicity Value -0.220
Molecular Weight (kDa) 50604.2
Isoelectric Point (pI) 5.90

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
3LR5 TRANSFERASE 02/10/10 Periplasmic domain of the risS sensor protein from Burkholderia pseudomallei, iodide phased at neutral pH BURKHOLDERIA PSEUDOMALLEI 2.3 X-RAY DIFFRACTION 97.5
3LR0 TRANSFERASE 02/10/10 Periplasmic domain of the risS sensor protein from Burkholderia pseudomallei, iodide phased at low pH BURKHOLDERIA PSEUDOMALLEI 1.9 X-RAY DIFFRACTION 97.5
3LR4 TRANSFERASE 02/10/10 Periplasmic domain of the risS sensor protein from Burkholderia pseudomallei, barium phased at low pH BURKHOLDERIA PSEUDOMALLEI 1.9 X-RAY DIFFRACTION 97.5
3LR3 TRANSFERASE 02/10/10 Periplasmic domain of the risS sensor protein from Burkholderia pesuromallei, low pH native structure BURKHOLDERIA PSEUDOMALLEI 2.1 X-RAY DIFFRACTION 97.5
3TE8 TRANSFERASE 08/12/11 Crystal structure of risS periplasmic domain at low pH dimer with N-termini ordered BURKHOLDERIA PSEUDOMALLEI 1.7 X-RAY DIFFRACTION 97.5

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 619 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG001802 (653 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BCAL2012

Human Homologs

References

No references are associated with this feature.