Burkholderia cenocepacia J2315, BCAM0984 (leuD)
Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
Gene Ontology
| Ontology | Accession | Term | GO Evidence | Evidence Ontology (ECO) Code | Reference | Comments |
|---|---|---|---|---|---|---|
| Molecular Function | GO:0003861 | 3-isopropylmalate dehydratase activity |
Inferred from Sequence Model
Term mapped from: InterPro:MF_01031
|
ECO:0000259 match to InterPro signature evidence used in automatic assertion |
||
| Cellular Component | GO:0009316 | 3-isopropylmalate dehydratase complex |
Inferred from Sequence Model
Term mapped from: InterPro:MF_01031
|
ECO:0000259 match to InterPro signature evidence used in automatic assertion |
||
| Biological Process | GO:0009098 | leucine biosynthetic process |
Inferred from Sequence Model
Term mapped from: InterPro:MF_01031
|
ECO:0000259 match to InterPro signature evidence used in automatic assertion |
Pathways
| Database | Xref | Pathway | Version | Evidence | PMID |
|---|---|---|---|---|---|
| KEGG | bcj00660 | C5-Branched dibasic acid metabolism | 73.0+/03-31, Mar 15 |
ECO:0000249
sequence similarity evidence used in automatic assertion |
|
| KEGG | bcj01230 | Biosynthesis of amino acids | 73.0+/03-31, Mar 15 |
ECO:0000249
sequence similarity evidence used in automatic assertion |
|
| KEGG (InterPro) | 00290 | Valine, leucine and isoleucine biosynthesis | InterPro 5.36-75.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
|
| KEGG | bcj01110 | Biosynthesis of secondary metabolites | 73.0+/03-31, Mar 15 |
ECO:0000249
sequence similarity evidence used in automatic assertion |
|
| KEGG | bcj00290 | Valine, leucine and isoleucine biosynthesis | 73.0+/03-31, Mar 15 |
ECO:0000249
sequence similarity evidence used in automatic assertion |
|
| KEGG | bcj01210 | 2-Oxocarboxylic acid metabolism | 73.0+/03-31, Mar 15 |
ECO:0000249
sequence similarity evidence used in automatic assertion |
|
| KEGG | bcj01100 | Metabolic pathways | 73.0+/03-31, Mar 15 |
ECO:0000249
sequence similarity evidence used in automatic assertion |
Functional Predictions from Interpro
| Analysis | Accession | Description | Interpro Accession | Interpro Description | Amino Acid Start | Amino Acid Stop | E-value |
|---|---|---|---|---|---|---|---|
| Hamap | MF_01031 | 3-isopropylmalate dehydratase small subunit [leuD]. | IPR004431 | 3-isopropylmalate dehydratase, small subunit | 1 | 210 | 44.43 |
| CDD | cd01577 | IPMI_Swivel | IPR033940 | 3-isopropylmalate dehydratase, swivel domain | 14 | 154 | 1.7218E-44 |
| SUPERFAMILY | SSF52016 | 1 | 201 | 3.53E-64 | |||
| Pfam | PF00694 | Aconitase C-terminal domain | IPR000573 | Aconitase A/isopropylmalate dehydratase small subunit, swivel domain | 1 | 132 | 2.7E-38 |
| TIGRFAM | TIGR00171 | leuD: 3-isopropylmalate dehydratase, small subunit | IPR004431 | 3-isopropylmalate dehydratase, small subunit | 1 | 196 | 5.6E-85 |
| Gene3D | G3DSA:3.20.19.10 | IPR015928 | Aconitase/3-isopropylmalate dehydratase, swivel | 1 | 188 | 1.1E-77 |
Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.