Burkholderia cenocepacia J2315, BCAM0715

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0004673 protein histidine kinase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01386
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016772 transferase activity, transferring phosphorus-containing groups
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PR00344
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Cellular Component GO:0016021 integral component of membrane
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PS50885
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Cellular Component GO:0016020 membrane
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01386
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0000155 phosphorelay sensor kinase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00512
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0016310 phosphorylation
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PR00344
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0007165 signal transduction
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00512
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0000160 phosphorelay signal transduction system
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01386
ECO:0000259
match to InterPro signature evidence used in automatic assertion

Pathways

Database Xref Pathway Version Evidence PMID
KEGG bcj02020 Two-component system 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
PRINTS PR00344 Bacterial sensor protein C-terminal signature IPR004358 Signal transduction histidine kinase-related protein, C-terminal 447 460 6.1E-18
TIGRFAM TIGR01386 cztS_silS_copS: heavy metal sensor kinase IPR006290 Heavy metal sensor kinase 7 460 7.2E-148
SUPERFAMILY SSF158472 192 239 4.84E-5
Pfam PF00672 HAMP domain IPR003660 HAMP domain 186 238 3.2E-8
SMART SM00304 IPR003660 HAMP domain 188 241 4.7E-8
ProSiteProfiles PS50109 Histidine kinase domain profile. IPR005467 Histidine kinase domain 249 463 43.915
CDD cd00075 HATPase 357 459 5.08964E-38
Pfam PF00512 His Kinase A (phospho-acceptor) domain IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain 243 307 9.0E-13
Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase IPR003594 Histidine kinase/HSP90-like ATPase 356 461 6.5E-23
ProSiteProfiles PS50885 HAMP domain profile. IPR003660 HAMP domain 188 241 8.864
PRINTS PR00344 Bacterial sensor protein C-terminal signature IPR004358 Signal transduction histidine kinase-related protein, C-terminal 388 402 6.1E-18
SMART SM00388 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain 242 308 1.2E-15
Gene3D G3DSA:1.10.287.130 192 309 4.5E-22
SUPERFAMILY SSF55874 IPR036890 Histidine kinase/HSP90-like ATPase superfamily 297 465 5.76E-43
Gene3D G3DSA:3.30.565.10 IPR036890 Histidine kinase/HSP90-like ATPase superfamily 314 466 1.0E-39
CDD cd06225 HAMP IPR003660 HAMP domain 191 238 1.03545E-5
CDD cd00082 HisKA IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain 242 304 2.36048E-14
PRINTS PR00344 Bacterial sensor protein C-terminal signature IPR004358 Signal transduction histidine kinase-related protein, C-terminal 423 441 6.1E-18
SUPERFAMILY SSF47384 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily 225 306 1.1E-16
PRINTS PR00344 Bacterial sensor protein C-terminal signature IPR004358 Signal transduction histidine kinase-related protein, C-terminal 406 416 6.1E-18
SMART SM00387 IPR003594 Histidine kinase/HSP90-like ATPase 351 463 7.6E-37

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.