Burkholderia cenocepacia J2315, BCAL3389 (tktA)

Gene Ontology

Ontology	Accession	Term	GO Evidence	Evidence Ontology (ECO) Code	Reference	Comments
Molecular Function	GO:0004802	transketolase activity	ISM Inferred from Sequence Model Term mapped from: InterPro:TIGR00232	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Molecular Function	GO:0003824	catalytic activity	ISM Inferred from Sequence Model Term mapped from: InterPro:SSF52922	ECO:0000259 match to InterPro signature evidence used in automatic assertion

Pathways

Database	Xref	Pathway	Version	Evidence	PMID
KEGG	bcj00710	Carbon fixation in photosynthetic organisms	73.0+/03-31, Mar 15	ECO:0000249 sequence similarity evidence used in automatic assertion
KEGG	bcj00030	Pentose phosphate pathway	73.0+/03-31, Mar 15	ECO:0000249 sequence similarity evidence used in automatic assertion
KEGG	bcj01230	Biosynthesis of amino acids	73.0+/03-31, Mar 15	ECO:0000249 sequence similarity evidence used in automatic assertion
KEGG	bcj01130	Biosynthesis of antibiotics	73.0+/03-31, Mar 15	ECO:0000249 sequence similarity evidence used in automatic assertion
KEGG	bcj01120	Microbial metabolism in diverse environments	73.0+/03-31, Mar 15	ECO:0000249 sequence similarity evidence used in automatic assertion
KEGG	bcj01100	Metabolic pathways	73.0+/03-31, Mar 15	ECO:0000249 sequence similarity evidence used in automatic assertion
KEGG	bcj01200	Carbon metabolism	73.0+/03-31, Mar 15	ECO:0000249 sequence similarity evidence used in automatic assertion
KEGG	bcj01110	Biosynthesis of secondary metabolites	73.0+/03-31, Mar 15	ECO:0000249 sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis	Accession	Description	Interpro Accession	Interpro Description	Amino Acid Start	Amino Acid Stop	E-value
SUPERFAMILY	SSF52518		IPR029061	Thiamin diphosphate-binding fold	22	338	3.21E-120
Gene3D	G3DSA:3.40.50.970				21	345	1.6E-131
SMART	SM00861		IPR005475	Transketolase-like, pyrimidine-binding domain	374	549	2.3E-63
SUPERFAMILY	SSF52922		IPR009014	Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II	556	690	1.83E-44
TIGRFAM	TIGR00232	tktlase_bact: transketolase	IPR005478	Transketolase, bacterial-like	27	689	5.3E-291
CDD	cd07033	TPP_PYR_DXS_TK_like			378	544	1.21765E-55
Gene3D	G3DSA:3.40.50.920		IPR009014	Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II	563	690	1.9E-43
Pfam	PF02780	Transketolase, C-terminal domain	IPR033248	Transketolase, C-terminal domain	577	681	3.0E-18
Pfam	PF00456	Transketolase, thiamine diphosphate binding domain	IPR005474	Transketolase, N-terminal	25	353	1.8E-160
CDD	cd02012	TPP_TK	IPR005474	Transketolase, N-terminal	29	293	2.28689E-144
Gene3D	G3DSA:3.40.50.970				346	561	1.7E-79
ProSitePatterns	PS00801	Transketolase signature 1.	IPR005474	Transketolase, N-terminal	32	52	-
SUPERFAMILY	SSF52518		IPR029061	Thiamin diphosphate-binding fold	370	549	2.14E-61
Pfam	PF02779	Transketolase, pyrimidine binding domain	IPR005475	Transketolase-like, pyrimidine-binding domain	373	547	2.1E-43

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.