Burkholderia cenocepacia J2315, BCAL2380 (kdpD)

Gene Ontology

Ontology	Accession	Term	GO Evidence	Evidence Ontology (ECO) Code	Reference	Comments
Biological Process	GO:0007165	signal transduction	ISM Inferred from Sequence Model Term mapped from: InterPro:PF00512	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Molecular Function	GO:0004673	protein histidine kinase activity	ISM Inferred from Sequence Model Term mapped from: InterPro:PF02702	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Molecular Function	GO:0016772	transferase activity, transferring phosphorus-containing groups	ISM Inferred from Sequence Model Term mapped from: InterPro:PR00344	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Molecular Function	GO:0005515	protein binding	ISM Inferred from Sequence Model Term mapped from: InterPro:PF13492	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Biological Process	GO:0016310	phosphorylation	ISM Inferred from Sequence Model Term mapped from: InterPro:PR00344	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Cellular Component	GO:0016020	membrane	ISM Inferred from Sequence Model Term mapped from: InterPro:PF02702	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Molecular Function	GO:0000155	phosphorelay sensor kinase activity	ISM Inferred from Sequence Model Term mapped from: InterPro:PF02702	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Biological Process	GO:0000160	phosphorelay signal transduction system	ISM Inferred from Sequence Model Term mapped from: InterPro:PF02702	ECO:0000259 match to InterPro signature evidence used in automatic assertion

Pathways

Database	Xref	Pathway	Version	Evidence	PMID
KEGG	bcj02020	Two-component system	73.0+/03-31, Mar 15	ECO:0000249 sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis	Accession	Description	Interpro Accession	Interpro Description	Amino Acid Start	Amino Acid Stop	E-value
PRINTS	PR00344	Bacterial sensor protein C-terminal signature	IPR004358	Signal transduction histidine kinase-related protein, C-terminal	903	916	1.1E-11
Gene3D	G3DSA:3.30.565.10		IPR036890	Histidine kinase/HSP90-like ATPase superfamily	764	922	1.4E-28
SUPERFAMILY	SSF52402				251	375	1.0E-6
Gene3D	G3DSA:3.30.450.40		IPR029016	GAF-like domain superfamily	521	670	1.3E-37
Pfam	PF13493	Domain of unknown function (DUF4118)	IPR025201	Sensor protein KdpD, transmembrane domain	411	517	2.9E-30
SUPERFAMILY	SSF47384		IPR036097	Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily	672	757	3.53E-14
PRINTS	PR00344	Bacterial sensor protein C-terminal signature	IPR004358	Signal transduction histidine kinase-related protein, C-terminal	841	855	1.1E-11
Pfam	PF02702	Osmosensitive K+ channel His kinase sensor domain	IPR003852	Signal transduction histidine kinase, osmosensitive K+ channel sensor, N-terminal	21	230	1.5E-98
PRINTS	PR00344	Bacterial sensor protein C-terminal signature	IPR004358	Signal transduction histidine kinase-related protein, C-terminal	874	892	1.1E-11
MobiDBLite	mobidb-lite	consensus disorder prediction			920	947	-
Pfam	PF02518	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	IPR003594	Histidine kinase/HSP90-like ATPase	804	918	1.2E-16
ProSiteProfiles	PS50109	Histidine kinase domain profile.	IPR005467	Histidine kinase domain	685	919	38.194
Pfam	PF13492	GAF domain	IPR003018	GAF domain	537	659	6.9E-16
PRINTS	PR00344	Bacterial sensor protein C-terminal signature	IPR004358	Signal transduction histidine kinase-related protein, C-terminal	859	869	1.1E-11
SMART	SM00387		IPR003594	Histidine kinase/HSP90-like ATPase	800	919	2.6E-30
CDD	cd00075	HATPase			805	915	1.1177E-28
SMART	SM00388		IPR003661	Signal transduction histidine kinase, dimerisation/phosphoacceptor domain	678	756	2.8E-15
SUPERFAMILY	SSF55781				515	662	7.41E-8
CDD	cd01987	USP_OKCHK			252	374	4.37989E-33
Gene3D	G3DSA:1.10.287.130				671	758	8.5E-17
Gene3D	G3DSA:3.40.50.300				19	229	8.9E-102
Gene3D	G3DSA:1.20.120.620		IPR038318	KdpD, transmembrane domain superfamily	408	511	7.9E-36
SUPERFAMILY	SSF55874		IPR036890	Histidine kinase/HSP90-like ATPase superfamily	746	919	1.28E-32
Pfam	PF00512	His Kinase A (phospho-acceptor) domain	IPR003661	Signal transduction histidine kinase, dimerisation/phosphoacceptor domain	680	756	1.9E-14
CDD	cd00082	HisKA	IPR003661	Signal transduction histidine kinase, dimerisation/phosphoacceptor domain	676	752	6.73837E-12

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.