Burkholderia cenocepacia J2315, BCAL2154 (lpxH)
Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
Gene Ontology
| Ontology | Accession | Term | GO Evidence | Evidence Ontology (ECO) Code | Reference | Comments |
|---|---|---|---|---|---|---|
| Biological Process | GO:0009245 | lipid A biosynthetic process |
Inferred from Sequence or Structural Similarity
Term mapped from: UniProtKB:P43341
|
ECO:0000303 non-traceable author statement used in manual assertion |
15610978 | Reviewed by curator |
| Molecular Function | GO:0016462 | pyrophosphatase activity |
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01854
|
ECO:0000259 match to InterPro signature evidence used in automatic assertion |
||
| Biological Process | GO:0009245 | lipid A biosynthetic process |
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01854
|
ECO:0000259 match to InterPro signature evidence used in automatic assertion |
||
| Cellular Component | GO:0005737 | cytoplasm |
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01854
|
ECO:0000259 match to InterPro signature evidence used in automatic assertion |
Pathways
| Database | Xref | Pathway | Version | Evidence | PMID |
|---|---|---|---|---|---|
| KEGG | bcj01100 | Metabolic pathways | 73.0+/03-31, Mar 15 |
ECO:0000249
sequence similarity evidence used in automatic assertion |
|
| KEGG | bcj00540 | Lipopolysaccharide biosynthesis | 73.0+/03-31, Mar 15 |
ECO:0000249
sequence similarity evidence used in automatic assertion |
|
| KEGG (InterPro) | 00540 | Lipopolysaccharide biosynthesis | InterPro 5.36-75.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
Functional Predictions from Interpro
| Analysis | Accession | Description | Interpro Accession | Interpro Description | Amino Acid Start | Amino Acid Stop | E-value |
|---|---|---|---|---|---|---|---|
| Coils | Coil | 265 | 266 | - | |||
| SUPERFAMILY | SSF56300 | 27 | 255 | 2.42E-29 | |||
| Hamap | MF_00575 | UDP-2,3-diacylglucosamine hydrolase [lpxH]. | IPR010138 | UDP-2,3-diacylglucosamine hydrolase | 1 | 266 | 99.508 |
| TIGRFAM | TIGR01854 | lipid_A_lpxH: UDP-2,3-diacylglucosamine diphosphatase | IPR010138 | UDP-2,3-diacylglucosamine hydrolase | 28 | 245 | 1.1E-69 |
| Pfam | PF12850 | Calcineurin-like phosphoesterase superfamily domain | IPR024654 | Calcineurin-like phosphoesterase domain, lpxH-type | 27 | 237 | 3.8E-8 |
| CDD | cd07398 | MPP_YbbF-LpxH | 28 | 241 | 1.15116E-54 |
Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.