Burkholderia cenocepacia J2315, BCAL2146 (ask)
Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
Gene Ontology
| Ontology | Accession | Term | GO Evidence | Evidence Ontology (ECO) Code | Reference | Comments |
|---|---|---|---|---|---|---|
| Biological Process | GO:0008652 | cellular amino acid biosynthetic process |
Inferred from Sequence Model
Term mapped from: InterPro:PS00324
|
ECO:0000259 match to InterPro signature evidence used in automatic assertion |
||
| Molecular Function | GO:0004072 | aspartate kinase activity |
Inferred from Sequence Model
Term mapped from: InterPro:PS00324
|
ECO:0000259 match to InterPro signature evidence used in automatic assertion |
||
| Biological Process | GO:0009089 | lysine biosynthetic process via diaminopimelate |
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00656
|
ECO:0000259 match to InterPro signature evidence used in automatic assertion |
Pathways
| Database | Xref | Pathway | Version | Evidence | PMID |
|---|---|---|---|---|---|
| KEGG | bcj01120 | Microbial metabolism in diverse environments | 73.0+/03-31, Mar 15 |
ECO:0000249
sequence similarity evidence used in automatic assertion |
|
| MetaCyc | 3-dehydroquinate biosynthesis II (archaea) | InterPro 5.36-75.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
||
| KEGG | bcj00260 | Glycine, serine and threonine metabolism | 73.0+/03-31, Mar 15 |
ECO:0000249
sequence similarity evidence used in automatic assertion |
|
| KEGG | bcj01110 | Biosynthesis of secondary metabolites | 73.0+/03-31, Mar 15 |
ECO:0000249
sequence similarity evidence used in automatic assertion |
|
| KEGG | bcj00300 | Lysine biosynthesis | 73.0+/03-31, Mar 15 |
ECO:0000249
sequence similarity evidence used in automatic assertion |
|
| KEGG | bcj01230 | Biosynthesis of amino acids | 73.0+/03-31, Mar 15 |
ECO:0000249
sequence similarity evidence used in automatic assertion |
|
| MetaCyc | norspermidine biosynthesis | InterPro 5.36-75.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
||
| KEGG (InterPro) | 00260 | Glycine, serine and threonine metabolism | InterPro 5.36-75.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
|
| MetaCyc | L-lysine biosynthesis III | InterPro 5.36-75.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
||
| KEGG | bcj00270 | Cysteine and methionine metabolism | 73.0+/03-31, Mar 15 |
ECO:0000249
sequence similarity evidence used in automatic assertion |
|
| KEGG (InterPro) | 00261 | Monobactam biosynthesis | InterPro 5.36-75.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
|
| KEGG | bcj01210 | 2-Oxocarboxylic acid metabolism | 73.0+/03-31, Mar 15 |
ECO:0000249
sequence similarity evidence used in automatic assertion |
|
| KEGG | bcj01130 | Biosynthesis of antibiotics | 73.0+/03-31, Mar 15 |
ECO:0000249
sequence similarity evidence used in automatic assertion |
|
| KEGG | bcj01100 | Metabolic pathways | 73.0+/03-31, Mar 15 |
ECO:0000249
sequence similarity evidence used in automatic assertion |
|
| MetaCyc | grixazone biosynthesis | InterPro 5.36-75.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
||
| MetaCyc | L-lysine biosynthesis II | InterPro 5.36-75.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
||
| KEGG (InterPro) | 00300 | Lysine biosynthesis | InterPro 5.36-75.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
|
| MetaCyc | spermidine biosynthesis II | InterPro 5.36-75.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
||
| MetaCyc | L-methionine biosynthesis IV (archaea) | InterPro 5.36-75.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
||
| KEGG (InterPro) | 00270 | Cysteine and methionine metabolism | InterPro 5.36-75.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
|
| MetaCyc | L-lysine biosynthesis VI | InterPro 5.36-75.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
Functional Predictions from Interpro
| Analysis | Accession | Description | Interpro Accession | Interpro Description | Amino Acid Start | Amino Acid Stop | E-value |
|---|---|---|---|---|---|---|---|
| SUPERFAMILY | SSF55021 | 342 | 414 | 3.49E-25 | |||
| Pfam | PF00696 | Amino acid kinase family | IPR001048 | Aspartate/glutamate/uridylate kinase | 3 | 229 | 3.3E-50 |
| TIGRFAM | TIGR00657 | asp_kinases: aspartate kinase | IPR001341 | Aspartate kinase | 63 | 412 | 4.8E-113 |
| TIGRFAM | TIGR00656 | asp_kin_monofn: aspartate kinase, monofunctional class | IPR005260 | Aspartate kinase, monofunctional class | 1 | 413 | 6.1E-129 |
| SUPERFAMILY | SSF55021 | 257 | 335 | 1.11E-17 | |||
| ProSiteProfiles | PS51671 | ACT domain profile. | IPR002912 | ACT domain | 355 | 417 | 12.972 |
| Pfam | PF13840 | ACT domain | IPR027795 | CASTOR, ACT domain | 348 | 409 | 2.4E-17 |
| PIRSF | PIRSF000726 | IPR005260 | Aspartate kinase, monofunctional class | 56 | 417 | 4.3E-142 | |
| SUPERFAMILY | SSF53633 | IPR036393 | Acetylglutamate kinase-like superfamily | 4 | 250 | 4.71E-73 | |
| Pfam | PF01842 | ACT domain | IPR002912 | ACT domain | 277 | 331 | 1.7E-9 |
| Gene3D | G3DSA:3.40.1160.10 | IPR036393 | Acetylglutamate kinase-like superfamily | 1 | 262 | 1.3E-86 | |
| Gene3D | G3DSA:3.30.70.260 | 263 | 413 | 5.1E-57 | |||
| PIRSF | PIRSF000726 | IPR005260 | Aspartate kinase, monofunctional class | 1 | 61 | 1.7E-23 | |
| Gene3D | G3DSA:3.30.70.260 | 270 | 348 | 5.1E-57 | |||
| ProSitePatterns | PS00324 | Aspartokinase signature. | IPR018042 | Aspartate kinase, conserved site | 5 | 13 | - |
| ProSiteProfiles | PS51671 | ACT domain profile. | IPR002912 | ACT domain | 274 | 349 | 11.335 |
| CDD | cd04261 | AAK_AKii-LysC-BS | IPR041740 | Aspartokinase catalytic domain | 3 | 250 | 3.89632E-134 |
| CDD | cd04923 | ACT_AK-LysC-DapG-like_2 | 360 | 413 | 1.75872E-27 | ||
| CDD | cd04913 | ACT_AKii-LysC-BS-like_1 | 271 | 346 | 1.59246E-27 |
Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.