Burkholderia cenocepacia J2315, BCAL2016 (ispD)

Gene Ontology

Ontology	Accession	Term	GO Evidence	Evidence Ontology (ECO) Code	Reference	Comments
Molecular Function	GO:0003824	catalytic activity	ISM Inferred from Sequence Model Term mapped from: InterPro:PS01295	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Molecular Function	GO:0050518	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity	ISM Inferred from Sequence Model Term mapped from: InterPro:TIGR00453	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Molecular Function	GO:0070567	cytidylyltransferase activity	ISM Inferred from Sequence Model Term mapped from: InterPro:PF01128	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Biological Process	GO:0008299	isoprenoid biosynthetic process	ISM Inferred from Sequence Model Term mapped from: InterPro:TIGR00453	ECO:0000259 match to InterPro signature evidence used in automatic assertion

Pathways

Database	Xref	Pathway	Version	Evidence	PMID
KEGG	bcj01100	Metabolic pathways	73.0+/03-31, Mar 15	ECO:0000249 sequence similarity evidence used in automatic assertion
KEGG	bcj01110	Biosynthesis of secondary metabolites	73.0+/03-31, Mar 15	ECO:0000249 sequence similarity evidence used in automatic assertion
KEGG	bcj00900	Terpenoid backbone biosynthesis	73.0+/03-31, Mar 15	ECO:0000249 sequence similarity evidence used in automatic assertion
KEGG (InterPro)	00900	Terpenoid backbone biosynthesis	InterPro 5.36-75.0	ECO:0000259 match to InterPro signature evidence used in automatic assertion
MetaCyc		methylerythritol phosphate pathway II	InterPro 5.36-75.0	ECO:0000259 match to InterPro signature evidence used in automatic assertion
KEGG	bcj01130	Biosynthesis of antibiotics	73.0+/03-31, Mar 15	ECO:0000249 sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis	Accession	Description	Interpro Accession	Interpro Description	Amino Acid Start	Amino Acid Stop	E-value
ProSitePatterns	PS01295	4-diphosphocytidyl-2C-methyl-D-erythritol synthase signature.	IPR018294	4-diphosphocytidyl-2C-methyl-D-erythritol synthase, conserved site	104	111	-
Hamap	MF_00108	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase [ispD].	IPR001228	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	4	229	43.759
CDD	cd02516	CDP-ME_synthetase	IPR034683	Cytidylyltransferase IspD/TarI	7	225	7.17481E-85
Pfam	PF01128	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	IPR034683	Cytidylyltransferase IspD/TarI	6	230	3.0E-61
SUPERFAMILY	SSF53448		IPR029044	Nucleotide-diphospho-sugar transferases	5	229	4.98E-53
Gene3D	G3DSA:3.90.550.10		IPR029044	Nucleotide-diphospho-sugar transferases	1	236	2.0E-80
TIGRFAM	TIGR00453	ispD: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	IPR001228	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	7	229	5.8E-66

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.