Burkholderia cenocepacia J2315, BCAL0881 (ntpA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0019177 dihydroneopterin triphosphate pyrophosphohydrolase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PR01404
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0008828 dATP pyrophosphohydrolase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PR01404
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016787 hydrolase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SSF55811
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0046656 folic acid biosynthetic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PR01404
ECO:0000259
match to InterPro signature evidence used in automatic assertion

Pathways

Database Xref Pathway Version Evidence PMID
MetaCyc 6-hydroxymethyl-dihydropterin diphosphate biosynthesis I InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG (InterPro) 00790 Folate biosynthesis InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
PRINTS PR01404 DATP pyrophosphohydrolase signature IPR003564 Dihydroneopterin triphosphate diphosphatase 5 22 1.2E-7
PRINTS PR01404 DATP pyrophosphohydrolase signature IPR003564 Dihydroneopterin triphosphate diphosphatase 76 95 1.2E-7
PRINTS PR01404 DATP pyrophosphohydrolase signature IPR003564 Dihydroneopterin triphosphate diphosphatase 133 146 1.2E-7
Gene3D G3DSA:3.90.79.10 2 153 4.4E-32
Pfam PF00293 NUDIX domain IPR000086 NUDIX hydrolase domain 9 145 5.2E-13
CDD cd04664 Nudix_Hydrolase_7 8 147 2.01401E-34
ProSiteProfiles PS51462 Nudix hydrolase domain profile. IPR000086 NUDIX hydrolase domain 6 150 14.596
SUPERFAMILY SSF55811 IPR015797 NUDIX hydrolase-like domain superfamily 3 150 2.44E-24

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.