Burkholderia cenocepacia J2315, BCAL0805 (mutM)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0006289 nucleotide-excision repair
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF06831
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006284 base-excision repair
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM00898
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003676 nucleic acid binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SSF46946
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0008270 zinc ion binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM00898
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003906 DNA-(apurinic or apyrimidinic site) endonuclease activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM00898
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003677 DNA binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PS01242
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM00898
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0008534 oxidized purine nucleobase lesion DNA N-glycosylase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_00103
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003684 damaged DNA binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM00898
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006281 DNA repair
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PS51066
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Pathways

Database Xref Pathway Version Evidence PMID
KEGG bcj03410 Base excision repair 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Hamap MF_00103 Formamidopyrimidine-DNA glycosylase [mutM]. IPR020629 Formamidopyrimidine-DNA glycosylase 1 275 42.444
Pfam PF06831 Formamidopyrimidine-DNA glycosylase H2TH domain IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding 135 225 2.7E-22
ProSiteProfiles PS51066 Zinc finger FPG-type profile. IPR000214 Zinc finger, DNA glycosylase/AP lyase-type 241 275 13.99
SUPERFAMILY SSF81624 IPR035937 MutM-like, N-terminal 2 144 8.63E-37
TIGRFAM TIGR00577 fpg: DNA-formamidopyrimidine glycosylase IPR020629 Formamidopyrimidine-DNA glycosylase 1 274 1.5E-84
CDD cd08966 EcFpg-like_N 2 120 2.89414E-45
ProSiteProfiles PS51068 Formamidopyrimidine-DNA glycosylase catalytic domain profile. IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain 2 114 31.636
Pfam PF06827 Zinc finger found in FPG and IleRS IPR010663 Zinc finger, FPG/IleRS-type 247 274 1.1E-11
SUPERFAMILY SSF57716 223 274 3.57E-18
Gene3D G3DSA:3.20.190.10 IPR035937 MutM-like, N-terminal 2 129 4.4E-35
SMART SM01232 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding 135 227 4.0E-43
Pfam PF01149 Formamidopyrimidine-DNA glycosylase N-terminal domain IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain 1 116 6.2E-31
ProSitePatterns PS01242 Zinc finger FPG-type signature. IPR015887 DNA glycosylase/AP lyase, zinc finger domain, DNA-binding site 250 274 -
SMART SM00898 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain 2 117 1.1E-46
SUPERFAMILY SSF46946 IPR010979 Ribosomal protein S13-like, H2TH 136 227 1.3E-25
Gene3D G3DSA:1.10.8.50 145 275 5.6E-44

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.