Burkholderia cenocepacia J2315, BCAL0770 (dnaE2)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0008408 3'-5' exonuclease activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF07733
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006260 DNA replication
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF07733
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003887 DNA-directed DNA polymerase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_01902
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003824 catalytic activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF02811
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
TIGRFAM TIGR00594 polc: DNA polymerase III, alpha subunit IPR004805 DNA polymerase III, alpha subunit 11 1013 6.0E-157
Hamap MF_01902 Error-prone DNA polymerase [dnaE2]. IPR023073 DNA polymerase, error-prone 10 1070 13.428
Pfam PF02811 PHP domain IPR004013 PHP domain 15 116 1.0E-13
Pfam PF07733 Bacterial DNA polymerase III alpha NTPase domain IPR011708 Bacterial DNA polymerase III, alpha subunit, NTPase domain 300 554 4.7E-77
SMART SM00481 IPR003141 Polymerase/histidinol phosphatase, N-terminal 11 78 8.1E-12
CDD cd07434 PHP_PolIIIA_DnaE2 10 287 3.78022E-107
SUPERFAMILY SSF89550 IPR016195 Polymerase/histidinol phosphatase-like 17 80 1.22E-6
CDD cd04485 DnaE_OBF 981 1058 5.18869E-15
Pfam PF14579 Helix-hairpin-helix motif IPR029460 DNA polymerase, helix-hairpin-helix motif 807 901 1.3E-22
Pfam PF17657 Bacterial DNA polymerase III alpha subunit finger domain IPR040982 DNA polymerase III alpha subunit finger domain 557 732 2.5E-56
Gene3D G3DSA:3.20.20.140 8 277 2.2E-48

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.