Burkholderia cenocepacia J2315, BCAL0129 (cheA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0004673 protein histidine kinase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM01231
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0000160 phosphorelay signal transduction system
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SSF47226
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0007165 signal transduction
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PS50851
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016772 transferase activity, transferring phosphorus-containing groups
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PR00344
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Cellular Component GO:0005737 cytoplasm
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM01231
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0016310 phosphorylation
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PR00344
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0000155 phosphorelay sensor kinase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SSF47384
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006935 chemotaxis
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PS50851
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Pathways

Database Xref Pathway Version Evidence PMID
KEGG bcj02020 Two-component system 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG bcj02030 Bacterial chemotaxis 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Pfam PF01584 CheW-like domain IPR002545 CheW-like domain 610 738 3.7E-23
PRINTS PR00344 Bacterial sensor protein C-terminal signature IPR004358 Signal transduction histidine kinase-related protein, C-terminal 549 559 1.2E-13
Gene3D G3DSA:2.30.30.40 605 733 1.5E-38
SMART SM01231 IPR004105 Histidine kinase CheA-like, homodimeric domain 357 420 7.3E-22
PRINTS PR00344 Bacterial sensor protein C-terminal signature IPR004358 Signal transduction histidine kinase-related protein, C-terminal 510 524 1.2E-13
SUPERFAMILY SSF47384 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily 358 421 2.0E-15
Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase IPR003594 Histidine kinase/HSP90-like ATPase 468 604 1.9E-16
Gene3D G3DSA:1.20.120.160 IPR036641 HPT domain superfamily 1 142 1.2E-43
CDD cd00731 CheA_reg 605 736 1.17532E-46
SUPERFAMILY SSF55874 IPR036890 Histidine kinase/HSP90-like ATPase superfamily 423 603 3.27E-35
ProSiteProfiles PS50894 Histidine-containing phosphotransfer (HPt) domain profile. IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 1 105 32.403
PRINTS PR00344 Bacterial sensor protein C-terminal signature IPR004358 Signal transduction histidine kinase-related protein, C-terminal 589 602 1.2E-13
SMART SM00260 IPR002545 CheW-like domain 597 737 2.7E-33
SMART SM00387 IPR003594 Histidine kinase/HSP90-like ATPase 465 605 1.1E-24
Coils Coil 396 423 -
CDD cd00088 HPT IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 5 102 5.24843E-22
ProSiteProfiles PS50109 Histidine kinase domain profile. IPR005467 Histidine kinase domain 397 605 20.93
Gene3D G3DSA:1.10.287.560 IPR037006 Histidine kinase CheA-like, homodimeric domain superfamily 357 420 3.5E-17
CDD cd16916 HATPase_CheA-like 428 602 4.87319E-91
Gene3D G3DSA:3.30.565.10 IPR036890 Histidine kinase/HSP90-like ATPase superfamily 421 604 1.2E-52
SUPERFAMILY SSF55052 IPR035891 CheY-binding domain of CheA 188 253 2.62E-20
SUPERFAMILY SSF50341 IPR036061 CheW-like domain superfamily 604 736 1.96E-29
Gene3D G3DSA:3.30.70.400 IPR035891 CheY-binding domain of CheA 175 253 1.0E-21
MobiDBLite mobidb-lite consensus disorder prediction 298 355 -
SMART SM00073 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 5 102 5.7E-34
ProSiteProfiles PS50851 CheW-like domain profile. IPR002545 CheW-like domain 607 742 23.54
Pfam PF02895 Signal transducing histidine kinase, homodimeric domain IPR004105 Histidine kinase CheA-like, homodimeric domain 358 420 1.6E-17
PRINTS PR00344 Bacterial sensor protein C-terminal signature IPR004358 Signal transduction histidine kinase-related protein, C-terminal 565 583 1.2E-13
Pfam PF09078 CheY binding IPR015162 CheY binding 190 252 2.7E-24
Gene3D G3DSA:2.40.50.180 628 692 1.5E-38
Pfam PF01627 Hpt domain IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 8 93 2.7E-19
SUPERFAMILY SSF47226 IPR036641 HPT domain superfamily 5 126 7.82E-33

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.