Burkholderia multivorans ATCC 17616, Bmul_2558 (ldhA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0051287 NAD binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF02826
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00389
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0055114 oxidation-reduction process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF02826
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Pathways

Database Xref Pathway Version Evidence PMID
KEGG bmu01120 Microbial metabolism in diverse environments - Burkholderia multivorans ATCC 17616 (JGI) 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG bmu00620 Pyruvate metabolism - Burkholderia multivorans ATCC 17616 (JGI) 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
CDD cd12183 LDH_like_2 1 324 0.0
Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 4 328 2.3E-31
SUPERFAMILY SSF51735 IPR036291 NAD(P)-binding domain superfamily 102 299 2.94E-61
SUPERFAMILY SSF52283 2 135 2.34E-40
Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain 110 298 2.6E-59
ProSitePatterns PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 195 217 -
Gene3D G3DSA:3.40.50.720 102 298 3.1E-137
ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 224 240 -
Gene3D G3DSA:3.40.50.720 5 322 3.1E-137

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.