Burkholderia thailandensis E264 ATCC 700388, BTH_II1222 (btaA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0017000 antibiotic biosynthetic process
IGC
Inferred from Genomic Context 		ECO:0000317
genomic context evidence used in manual assertion		 20095633 Reviewed by curator
Biological Process GO:0055114 oxidation-reduction process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PIRSF009283
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003868 4-hydroxyphenylpyruvate dioxygenase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PIRSF009283
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PIRSF009283
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0009072 aromatic amino acid family metabolic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PIRSF009283
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Pathways

Database Xref Pathway Version Evidence PMID
KEGG bte00350 Tyrosine metabolism 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG bte01100 Metabolic pathways 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG bte00130 Ubiquinone and other terpenoid-quinone biosynthesis 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG bte00360 Phenylalanine metabolism 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Pfam PF14696 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal 20 166 8.0E-49
ProSiteProfiles PS51819 Vicinal oxygen chelate (VOC) domain profile. IPR037523 Vicinal oxygen chelate (VOC) domain 187 354 20.78
PIRSF PIRSF009283 IPR005956 4-hydroxyphenylpyruvate dioxygenase 12 381 1.5E-101
CDD cd07250 HPPD_C_like IPR041735 4-hydroxyphenylpyruvate dioxygenase, C-terminal 185 371 2.61003E-63
ProSiteProfiles PS51819 Vicinal oxygen chelate (VOC) domain profile. IPR037523 Vicinal oxygen chelate (VOC) domain 27 145 16.478
Gene3D G3DSA:3.10.180.10 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase 183 379 2.5E-46
Gene3D G3DSA:3.10.180.10 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase 19 176 9.5E-44
SUPERFAMILY SSF54593 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase 20 368 9.19E-68
Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain 188 299 4.4E-15
CDD cd08342 HPPD_N_like IPR041736 4-hydroxyphenylpyruvate dioxygenase, N-terminal 29 168 5.35369E-28

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.