Burkholderia thailandensis E264 ATCC 700388, BTH_II0687 (metZ)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0003824 catalytic activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:G3DSA:3.40.640.10
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0071268 homocysteine biosynthetic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_02056
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0019346 transsulfuration
ISM
Inferred from Sequence Model
Term mapped from: InterPro:cd00614
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0030170 pyridoxal phosphate binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:cd00614
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0030170 pyridoxal phosphate binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:cd00614
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0019346 transsulfuration
ISM
Inferred from Sequence Model
Term mapped from: InterPro:cd00614
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003824 catalytic activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:G3DSA:3.40.640.10
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0071268 homocysteine biosynthetic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_02056
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Pathways

Database Xref Pathway Version Evidence PMID
KEGG bte01100 Metabolic pathways 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG bte00270 Cysteine and methionine metabolism 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG bte00920 Sulfur metabolism 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
SUPERFAMILY SSF53383 IPR015424 Pyridoxal phosphate-dependent transferase 38 404 1.75E-119
TIGRFAM TIGR01325 O_suc_HS_sulf: O-succinylhomoserine sulfhydrylase IPR006234 O-succinylhomoserine sulfhydrylase 17 403 5.7E-174
ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme 208 222 -
Hamap MF_02056 O-succinylhomoserine sulfhydrylase [metZ]. IPR006234 O-succinylhomoserine sulfhydrylase 18 404 55.053
PIRSF PIRSF001434 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme 3 405 9.6E-132
Gene3D G3DSA:3.90.1150.10 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 267 405 4.2E-50
Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme 17 403 1.4E-137
Gene3D G3DSA:3.40.640.10 IPR015421 Pyridoxal phosphate-dependent transferase, major domain 15 266 1.1E-85
CDD cd00614 CGS_like IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme 37 404 5.09236E-160

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.