Burkholderia thailandensis E264 ATCC 700388, BTH_II0681 (trpA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0003824 catalytic activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SSF51366
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0004834 tryptophan synthase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_00131
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003824 catalytic activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SSF51366
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006568 tryptophan metabolic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_00131
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006568 tryptophan metabolic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_00131
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0004834 tryptophan synthase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_00131
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Pathways

Database Xref Pathway Version Evidence PMID
KEGG (InterPro) 00260 Glycine, serine and threonine metabolism InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG bte00400 Phenylalanine, tyrosine and tryptophan biosynthesis 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG bte00260 Glycine, serine and threonine metabolism 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG bte01230 Biosynthesis of amino acids 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG bte01100 Metabolic pathways 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG bte01110 Biosynthesis of secondary metabolites 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG (InterPro) 00400 Phenylalanine, tyrosine and tryptophan biosynthesis InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Pfam PF00290 Tryptophan synthase alpha chain IPR002028 Tryptophan synthase, alpha chain 8 259 6.4E-88
CDD cd04724 Tryptophan_synthase_alpha IPR002028 Tryptophan synthase, alpha chain 18 260 1.38184E-103
TIGRFAM TIGR00262 trpA: tryptophan synthase, alpha subunit IPR002028 Tryptophan synthase, alpha chain 8 259 5.4E-76
ProSitePatterns PS00167 Tryptophan synthase alpha chain signature. IPR018204 Tryptophan synthase, alpha chain, active site 48 61 -
Gene3D G3DSA:3.20.20.70 IPR013785 Aldolase-type TIM barrel 1 268 3.5E-102
Hamap MF_00131 Tryptophan synthase alpha chain [trpA]. IPR002028 Tryptophan synthase, alpha chain 14 262 35.135
SUPERFAMILY SSF51366 IPR011060 Ribulose-phosphate binding barrel 1 252 3.86E-91

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.