Burkholderia pseudomallei K96243, BPSL3187 (rpoA)

Gene Ontology

Ontology	Accession	Term	GO Evidence	Evidence Ontology (ECO) Code	Reference	Comments
Molecular Function	GO:0003677	DNA binding	ISM Inferred from Sequence Model Term mapped from: InterPro:MF_00059	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Molecular Function	GO:0003899	DNA-directed 5'-3' RNA polymerase activity	ISM Inferred from Sequence Model Term mapped from: InterPro:PF01193	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Molecular Function	GO:0046983	protein dimerization activity	ISM Inferred from Sequence Model Term mapped from: InterPro:PF01000	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Biological Process	GO:0006351	transcription, DNA-templated	ISM Inferred from Sequence Model Term mapped from: InterPro:PF01193	ECO:0000259 match to InterPro signature evidence used in automatic assertion

Pathways

Database	Xref	Pathway	Version	Evidence	PMID
KEGG	bps03020	RNA polymerase	73.0+/03-31, Mar 15	ECO:0000249 sequence similarity evidence used in automatic assertion
KEGG	bps01100	Metabolic pathways	73.0+/03-31, Mar 15	ECO:0000249 sequence similarity evidence used in automatic assertion
KEGG	bps00230	Purine metabolism	73.0+/03-31, Mar 15	ECO:0000249 sequence similarity evidence used in automatic assertion
KEGG	bps00240	Pyrimidine metabolism	73.0+/03-31, Mar 15	ECO:0000249 sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis	Accession	Description	Interpro Accession	Interpro Description	Amino Acid Start	Amino Acid Stop	E-value
Hamap	MF_00059	DNA-directed RNA polymerase subunit alpha [rpoA].	IPR011773	DNA-directed RNA polymerase, alpha subunit	2	314	35.125
Gene3D	G3DSA:2.170.120.12		IPR036643	DNA-directed RNA polymerase, insert domain superfamily	50	173	5.3E-81
SUPERFAMILY	SSF55257		IPR036603	RNA polymerase, RBP11-like subunit	5	228	1.77E-31
CDD	cd06928	RNAP_alpha_NTD			13	227	8.62392E-107
TIGRFAM	TIGR02027	rpoA: DNA-directed RNA polymerase, alpha subunit	IPR011773	DNA-directed RNA polymerase, alpha subunit	21	313	4.8E-106
Pfam	PF01193	RNA polymerase Rpb3/Rpb11 dimerisation domain	IPR011263	DNA-directed RNA polymerase, RpoA/D/Rpb3-type	26	224	5.4E-22
SMART	SM00662		IPR011263	DNA-directed RNA polymerase, RpoA/D/Rpb3-type	20	230	1.3E-93
SUPERFAMILY	SSF56553		IPR036643	DNA-directed RNA polymerase, insert domain superfamily	50	174	5.23E-41
Gene3D	G3DSA:3.30.1360.10		IPR036603	RNA polymerase, RBP11-like subunit	14	223	5.3E-81
Gene3D	G3DSA:1.10.150.20				242	325	1.6E-37
Pfam	PF01000	RNA polymerase Rpb3/RpoA insert domain	IPR011262	DNA-directed RNA polymerase, insert domain	61	150	1.7E-23
Pfam	PF03118	Bacterial RNA polymerase, alpha chain C terminal domain	IPR011260	RNA polymerase, alpha subunit, C-terminal	248	305	9.3E-25
SUPERFAMILY	SSF47789				248	320	5.23E-27

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.