Burkholderia pseudomallei K96243, BPSL2928 (purB)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0006188 IMP biosynthetic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF08328
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003824 catalytic activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PS00163
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0009152 purine ribonucleotide biosynthetic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00928
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0004018 N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF08328
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Pathways

Database Xref Pathway Version Evidence PMID
KEGG bps01130 Biosynthesis of antibiotics 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG (InterPro) 00230 Purine metabolism InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
MetaCyc inosine-5'-phosphate biosynthesis II InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG bps00230 Purine metabolism 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
MetaCyc inosine-5'-phosphate biosynthesis I InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG (InterPro) 00250 Alanine, aspartate and glutamate metabolism InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG bps01110 Biosynthesis of secondary metabolites 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG bps01100 Metabolic pathways 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG bps00250 Alanine, aspartate and glutamate metabolism 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
MetaCyc inosine-5'-phosphate biosynthesis III InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
MetaCyc adenosine ribonucleotides <i>de novo</i> biosynthesis InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
CDD cd01598 PurB 50 473 0.0
Gene3D G3DSA:1.10.40.30 409 472 3.2E-150
PRINTS PR00149 Fumarate lyase superfamily signature IPR000362 Fumarate lyase family 143 161 2.9E-18
Coils Coil 210 230 -
TIGRFAM TIGR00928 purB: adenylosuccinate lyase IPR004769 Adenylosuccinate lyase 39 482 1.9E-125
PRINTS PR00149 Fumarate lyase superfamily signature IPR000362 Fumarate lyase family 321 337 2.9E-18
PRINTS PR00149 Fumarate lyase superfamily signature IPR000362 Fumarate lyase family 189 207 2.9E-18
Pfam PF08328 Adenylosuccinate lyase C-terminal IPR013539 Adenylosuccinate lyase PurB, C-terminal 358 472 2.3E-51
ProSitePatterns PS00163 Fumarate lyases signature. IPR020557 Fumarate lyase, conserved site 321 330 -
SUPERFAMILY SSF48557 IPR008948 L-Aspartase-like 28 474 2.51E-106
Gene3D G3DSA:1.10.275.10 IPR024083 Fumarase/histidase, N-terminal 21 143 5.1E-42
Pfam PF00206 Lyase IPR022761 Fumarate lyase, N-terminal 41 339 1.1E-58
Gene3D G3DSA:1.20.200.10 144 473 3.2E-150
PRINTS PR00149 Fumarate lyase superfamily signature IPR000362 Fumarate lyase family 278 305 2.9E-18

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.