Burkholderia pseudomallei K96243, BPSL2690 (pyrB)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0004070 aspartate carbamoyltransferase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_00001
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016597 amino acid binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:G3DSA:3.40.50.1370
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006207 'de novo' pyrimidine nucleobase biosynthetic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_00001
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016743 carboxyl- or carbamoyltransferase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:G3DSA:3.40.50.1370
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006520 cellular amino acid metabolic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:G3DSA:3.40.50.1370
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Pathways

Database Xref Pathway Version Evidence PMID
KEGG (InterPro) 00240 Pyrimidine metabolism InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG bps01100 Metabolic pathways 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG bps00250 Alanine, aspartate and glutamate metabolism 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
MetaCyc UMP biosynthesis III InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG (InterPro) 00250 Alanine, aspartate and glutamate metabolism InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG bps00240 Pyrimidine metabolism 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
MetaCyc UMP biosynthesis I InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
MetaCyc UMP biosynthesis II InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature IPR006130 Aspartate/ornithine carbamoyltransferase 85 104 4.9E-19
PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature IPR006130 Aspartate/ornithine carbamoyltransferase 304 327 4.9E-19
Hamap MF_00001 Aspartate carbamoyltransferase [pyrB]. IPR002082 Aspartate carbamoyltransferase 38 341 41.018
TIGRFAM TIGR00670 asp_carb_tr: aspartate carbamoyltransferase IPR002082 Aspartate carbamoyltransferase 39 338 2.8E-90
PRINTS PR00101 Aspartate carbamoyltransferase signature 75 97 2.6E-28
PRINTS PR00101 Aspartate carbamoyltransferase signature 170 187 2.6E-28
Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding 39 183 9.4E-40
Gene3D G3DSA:3.40.50.1370 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily 171 318 2.7E-89
Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain 192 335 4.1E-23
PRINTS PR00101 Aspartate carbamoyltransferase signature 255 264 2.6E-28
PRINTS PR00101 Aspartate carbamoyltransferase signature 113 122 2.6E-28
SUPERFAMILY SSF53671 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily 38 340 1.7E-93
PRINTS PR00101 Aspartate carbamoyltransferase signature 296 301 2.6E-28
PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature IPR006130 Aspartate/ornithine carbamoyltransferase 292 301 4.9E-19
ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. IPR006130 Aspartate/ornithine carbamoyltransferase 85 92 -
PRINTS PR00101 Aspartate carbamoyltransferase signature 320 334 2.6E-28
PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature IPR006130 Aspartate/ornithine carbamoyltransferase 171 182 4.9E-19
Gene3D G3DSA:3.40.50.1370 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily 44 334 2.7E-89

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.