Burkholderia pseudomallei K96243, BPSL2686 (rmlB)
Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
Gene Ontology
| Ontology | Accession | Term | GO Evidence | Evidence Ontology (ECO) Code | Reference | Comments |
|---|---|---|---|---|---|---|
| Biological Process | GO:0009225 | nucleotide-sugar metabolic process |
Inferred from Sequence Model
Term mapped from: InterPro:cd05246
|
ECO:0000259 match to InterPro signature evidence used in automatic assertion |
||
| Molecular Function | GO:0008460 | dTDP-glucose 4,6-dehydratase activity |
Inferred from Sequence Model
Term mapped from: InterPro:cd05246
|
ECO:0000259 match to InterPro signature evidence used in automatic assertion |
Pathways
| Database | Xref | Pathway | Version | Evidence | PMID |
|---|---|---|---|---|---|
| MetaCyc | dTDP-D-olivose, dTDP-D-oliose and dTDP-D-mycarose biosynthesis | InterPro 5.36-75.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
||
| MetaCyc | dTDP-α-D-mycaminose biosynthesis | InterPro 5.36-75.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
||
| MetaCyc | dTDP-β-L-4-<i>epi</i>-vancosamine biosynthesis | InterPro 5.36-75.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
||
| MetaCyc | dTDP-L-megosamine biosynthesis | InterPro 5.36-75.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
||
| MetaCyc | dTDP-D-forosamine biosynthesis | InterPro 5.36-75.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
||
| KEGG (InterPro) | 00525 | Acarbose and validamycin biosynthesis | InterPro 5.36-75.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
|
| KEGG | bps00521 | Streptomycin biosynthesis | 73.0+/03-31, Mar 15 |
ECO:0000249
sequence similarity evidence used in automatic assertion |
|
| MetaCyc | dTDP-D-β-fucofuranose biosynthesis | InterPro 5.36-75.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
||
| KEGG | bps00523 | Polyketide sugar unit biosynthesis | 73.0+/03-31, Mar 15 |
ECO:0000249
sequence similarity evidence used in automatic assertion |
|
| KEGG (InterPro) | 00521 | Streptomycin biosynthesis | InterPro 5.36-75.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
|
| MetaCyc | dTDP-L-mycarose biosynthesis | InterPro 5.36-75.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
||
| MetaCyc | dTDP-<i>N</i>-acetylthomosamine biosynthesis | InterPro 5.36-75.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
||
| MetaCyc | dTDP-<i>N</i>-acetylviosamine biosynthesis | InterPro 5.36-75.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
||
| MetaCyc | dTDP-6-deoxy-α-D-allose biosynthesis | InterPro 5.36-75.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
||
| MetaCyc | dTDP-3-acetamido-α-D-fucose biosynthesis | InterPro 5.36-75.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
||
| MetaCyc | dTDP-D-desosamine biosynthesis | InterPro 5.36-75.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
||
| MetaCyc | dTDP-D-ravidosamine and dTDP-4-acetyl-D-ravidosamine biosynthesis | InterPro 5.36-75.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
||
| MetaCyc | dTDP-4-<i>O</i>-demethyl-β-L-noviose biosynthesis | InterPro 5.36-75.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
||
| MetaCyc | dTDP-3-acetamido-3,6-dideoxy-α-D-glucose biosynthesis | InterPro 5.36-75.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
||
| KEGG | bps01130 | Biosynthesis of antibiotics | 73.0+/03-31, Mar 15 |
ECO:0000249
sequence similarity evidence used in automatic assertion |
|
| MetaCyc | dTDP-L-daunosamine biosynthesis | InterPro 5.36-75.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
||
| KEGG | bps01110 | Biosynthesis of secondary metabolites | 73.0+/03-31, Mar 15 |
ECO:0000249
sequence similarity evidence used in automatic assertion |
|
| KEGG | bps01100 | Metabolic pathways | 73.0+/03-31, Mar 15 |
ECO:0000249
sequence similarity evidence used in automatic assertion |
|
| MetaCyc | dTDP-β-L-digitoxose biosynthesis | InterPro 5.36-75.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
||
| KEGG (InterPro) | 00523 | Polyketide sugar unit biosynthesis | InterPro 5.36-75.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
|
| MetaCyc | dTDP-L-olivose biosynthesis | InterPro 5.36-75.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
Functional Predictions from Interpro
| Analysis | Accession | Description | Interpro Accession | Interpro Description | Amino Acid Start | Amino Acid Stop | E-value |
|---|---|---|---|---|---|---|---|
| Gene3D | G3DSA:3.40.50.720 | 2 | 321 | 2.5E-130 | |||
| CDD | cd05246 | dTDP_GD_SDR_e | IPR005888 | dTDP-glucose 4,6-dehydratase | 2 | 331 | 0.0 |
| SUPERFAMILY | SSF51735 | IPR036291 | NAD(P)-binding domain superfamily | 2 | 333 | 3.04E-90 | |
| Pfam | PF16363 | GDP-mannose 4,6 dehydratase | IPR016040 | NAD(P)-binding domain | 3 | 322 | 2.3E-100 |
| Gene3D | G3DSA:3.90.25.10 | 200 | 329 | 2.5E-130 | |||
| TIGRFAM | TIGR01181 | dTDP_gluc_dehyt: dTDP-glucose 4,6-dehydratase | IPR005888 | dTDP-glucose 4,6-dehydratase | 2 | 335 | 9.4E-153 |
Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.