Burkholderia pseudomallei K96243, BPSL2153 (dxr)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0030604 1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PIRSF006205
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0055114 oxidation-reduction process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF02670
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0030604 1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PIRSF006205
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0005515 protein binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF08436
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0046872 metal ion binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PIRSF006205
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0008299 isoprenoid biosynthetic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PIRSF006205
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0070402 NADPH binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF02670
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0046872 metal ion binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PIRSF006205
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0008299 isoprenoid biosynthetic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PIRSF006205
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0055114 oxidation-reduction process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF02670
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0070402 NADPH binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF02670
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0005515 protein binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF08436
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Pathways

Database Xref Pathway Version Evidence PMID
MetaCyc methylerythritol phosphate pathway II InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG bps01100 Metabolic pathways 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG (InterPro) 00900 Terpenoid backbone biosynthesis InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG bps01110 Biosynthesis of secondary metabolites 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG bps00900 Terpenoid backbone biosynthesis 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG bps01130 Biosynthesis of antibiotics 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
SUPERFAMILY SSF55347 127 267 2.16E-60
Gene3D G3DSA:1.10.1740.10 305 391 1.1E-29
SUPERFAMILY SSF51735 IPR036291 NAD(P)-binding domain superfamily 3 151 6.4E-44
Pfam PF13288 DXP reductoisomerase C-terminal domain IPR026877 DXP reductoisomerase C-terminal domain 264 380 1.5E-41
Hamap MF_00183 1-deoxy-D-xylulose 5-phosphate reductoisomerase [dxr]. IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase 5 385 46.328
PIRSF PIRSF006205 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase 2 391 3.7E-154
Pfam PF08436 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal domain IPR013644 1-deoxy-D-xylulose 5-phosphate reductoisomerase, C-terminal 147 232 1.4E-39
SUPERFAMILY SSF69055 IPR036169 DXP reductoisomerase, C-terminal domain superfamily 295 388 3.92E-31
Gene3D G3DSA:3.40.50.720 1 151 4.5E-52
Pfam PF02670 1-deoxy-D-xylulose 5-phosphate reductoisomerase IPR013512 1-deoxy-D-xylulose 5-phosphate reductoisomerase, N-terminal 5 133 4.0E-44
TIGRFAM TIGR00243 Dxr: 1-deoxy-D-xylulose 5-phosphate reductoisomerase IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase 2 382 9.2E-154

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.