Burkholderia pseudomallei K96243, BPSL2099 (ispD)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0050518 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00453
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0008299 isoprenoid biosynthetic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PS01295
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0050518 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00453
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003824 catalytic activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PS01295
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003824 catalytic activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PS01295
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0008299 isoprenoid biosynthetic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PS01295
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0070567 cytidylyltransferase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:cd02516
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0070567 cytidylyltransferase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:cd02516
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Pathways

Database Xref Pathway Version Evidence PMID
MetaCyc methylerythritol phosphate pathway II InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG bps01130 Biosynthesis of antibiotics 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG (InterPro) 00900 Terpenoid backbone biosynthesis InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG bps01100 Metabolic pathways 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG bps01110 Biosynthesis of secondary metabolites 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG bps00900 Terpenoid backbone biosynthesis 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
TIGRFAM TIGR00453 ispD: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 7 229 1.7E-66
ProSitePatterns PS01295 4-diphosphocytidyl-2C-methyl-D-erythritol synthase signature. IPR018294 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, conserved site 104 111 -
Pfam PF01128 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase IPR034683 Cytidylyltransferase IspD/TarI 6 230 4.0E-61
Gene3D G3DSA:3.90.550.10 IPR029044 Nucleotide-diphospho-sugar transferases 1 236 3.0E-82
Hamap MF_00108 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase [ispD]. IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 4 229 43.25
SUPERFAMILY SSF53448 IPR029044 Nucleotide-diphospho-sugar transferases 5 229 6.76E-54
CDD cd02516 CDP-ME_synthetase IPR034683 Cytidylyltransferase IspD/TarI 7 225 5.4121E-88

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.