Burkholderia pseudomallei K96243, BPSL2095

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0000155 phosphorelay sensor kinase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM00388
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016772 transferase activity, transferring phosphorus-containing groups
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PR00344
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0007165 signal transduction
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM00388
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016772 transferase activity, transferring phosphorus-containing groups
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PR00344
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0016310 phosphorylation
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PR00344
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0016310 phosphorylation
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PR00344
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0007165 signal transduction
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM00388
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Cellular Component GO:0016021 integral component of membrane
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PS50885
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Cellular Component GO:0016021 integral component of membrane
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PS50885
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0000155 phosphorelay sensor kinase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM00388
ECO:0000259
match to InterPro signature evidence used in automatic assertion

Pathways

Database Xref Pathway Version Evidence PMID
KEGG bps02020 Two-component system 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
CDD cd00075 HATPase 336 443 2.50539E-25
Gene3D G3DSA:3.30.565.10 IPR036890 Histidine kinase/HSP90-like ATPase superfamily 293 450 1.1E-30
Pfam PF00512 His Kinase A (phospho-acceptor) domain IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain 237 289 9.1E-7
SUPERFAMILY SSF47384 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily 219 290 1.08E-11
SMART SM00387 IPR003594 Histidine kinase/HSP90-like ATPase 331 447 6.1E-28
SUPERFAMILY SSF55874 IPR036890 Histidine kinase/HSP90-like ATPase superfamily 286 445 3.8E-32
PRINTS PR00344 Bacterial sensor protein C-terminal signature IPR004358 Signal transduction histidine kinase-related protein, C-terminal 390 400 1.2E-9
Gene3D G3DSA:3.30.450.300 IPR038421 Sensor histidine kinase RisS, periplasmic domain superfamily 33 158 1.2E-53
ProSiteProfiles PS50885 HAMP domain profile. IPR003660 HAMP domain 181 233 7.727
Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase IPR003594 Histidine kinase/HSP90-like ATPase 332 445 4.1E-17
CDD cd06225 HAMP IPR003660 HAMP domain 183 230 0.00818442
PRINTS PR00344 Bacterial sensor protein C-terminal signature IPR004358 Signal transduction histidine kinase-related protein, C-terminal 406 424 1.2E-9
Coils Coil 214 234 -
ProSiteProfiles PS50109 Histidine kinase domain profile. IPR005467 Histidine kinase domain 241 447 39.532
CDD cd00082 HisKA IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain 232 289 1.00735E-7
PRINTS PR00344 Bacterial sensor protein C-terminal signature IPR004358 Signal transduction histidine kinase-related protein, C-terminal 372 386 1.2E-9
Gene3D G3DSA:1.10.287.130 179 289 1.3E-17
SMART SM00304 IPR003660 HAMP domain 181 233 2.5E-4
SMART SM00388 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain 234 293 9.6E-8
Pfam PF16524 Periplasmic domain of Sensor histidine kinase RisS IPR032408 Sensor histidine kinase RisS, periplasmic domain 47 152 2.0E-40

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.