Burkholderia pseudomallei K96243, BPSL1945 (thrS)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0004829 threonine-tRNA ligase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_00184
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0000166 nucleotide binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00587
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Cellular Component GO:0005737 cytoplasm
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_00184
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006435 threonyl-tRNA aminoacylation
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_00184
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0005524 ATP binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00587
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0004812 aminoacyl-tRNA ligase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00587
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006418 tRNA aminoacylation for protein translation
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00587
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0043039 tRNA aminoacylation
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM00863
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Pathways

Database Xref Pathway Version Evidence PMID
KEGG (InterPro) 00970 Aminoacyl-tRNA biosynthesis InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG bps00970 Aminoacyl-tRNA biosynthesis 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
CDD cd01667 TGS_ThrRS 2 66 7.54758E-24
Gene3D G3DSA:3.40.50.800 IPR036621 Anticodon-binding domain superfamily 531 634 4.3E-29
Gene3D G3DSA:3.30.930.10 222 530 2.5E-131
PRINTS PR01047 Threonyl-tRNA synthetase signature IPR002320 Threonine-tRNA ligase, class IIa 328 356 4.2E-53
PRINTS PR01047 Threonyl-tRNA synthetase signature IPR002320 Threonine-tRNA ligase, class IIa 506 519 4.2E-53
SUPERFAMILY SSF81271 IPR012676 TGS-like 2 61 1.24E-14
Gene3D G3DSA:3.30.980.10 69 221 2.0E-65
Gene3D G3DSA:3.10.20.30 IPR012675 Beta-grasp domain superfamily 1 63 7.0E-23
Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain IPR012947 Threonyl/alanyl tRNA synthetase, SAD 170 218 2.9E-15
Hamap MF_00184 Threonine--tRNA ligase [thrS]. IPR002320 Threonine-tRNA ligase, class IIa 66 633 34.797
Gene3D G3DSA:3.30.54.20 130 186 2.0E-65
Pfam PF02824 TGS domain IPR004095 TGS 4 61 4.1E-7
ProSiteProfiles PS50862 Aminoacyl-transfer RNA synthetases class-II family profile. IPR006195 Aminoacyl-tRNA synthetase, class II 242 533 32.441
PRINTS PR01047 Threonyl-tRNA synthetase signature IPR002320 Threonine-tRNA ligase, class IIa 361 384 4.2E-53
Pfam PF03129 Anticodon binding domain IPR004154 Anticodon-binding 540 629 2.0E-18
PRINTS PR01047 Threonyl-tRNA synthetase signature IPR002320 Threonine-tRNA ligase, class IIa 463 491 4.2E-53
CDD cd00860 ThrRS_anticodon 538 628 7.56476E-38
SUPERFAMILY SSF55681 242 525 2.87E-104
SUPERFAMILY SSF55186 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily 64 240 8.24E-70
TIGRFAM TIGR00418 thrS: threonine--tRNA ligase IPR002320 Threonine-tRNA ligase, class IIa 72 630 7.9E-225
Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) 318 528 1.8E-43
CDD cd00771 ThrRS_core IPR033728 Threonine-tRNA ligase catalytic core domain 241 538 2.05692E-179
SMART SM00863 IPR012947 Threonyl/alanyl tRNA synthetase, SAD 169 218 2.1E-24
SUPERFAMILY SSF52954 529 632 3.47E-29
PRINTS PR01047 Threonyl-tRNA synthetase signature IPR002320 Threonine-tRNA ligase, class IIa 533 545 4.2E-53

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.