Burkholderia pseudomallei K96243, BPSL1349 (carA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0004088 carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_01209
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006541 glutamine metabolic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_01209
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006207 'de novo' pyrimidine nucleobase biosynthetic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_01209
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Pathways

Database Xref Pathway Version Evidence PMID
KEGG bps01100 Metabolic pathways 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG bps00250 Alanine, aspartate and glutamate metabolism 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
MetaCyc L-arginine biosynthesis III (via <i>N</i>-acetyl-L-citrulline) InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
MetaCyc L-arginine biosynthesis IV (archaebacteria) InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
MetaCyc UMP biosynthesis II InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG (InterPro) 00250 Alanine, aspartate and glutamate metabolism InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG (InterPro) 00240 Pyrimidine metabolism InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG bps00240 Pyrimidine metabolism 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
MetaCyc UMP biosynthesis I InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
MetaCyc UMP biosynthesis III InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
TIGRFAM TIGR01368 CPSaseIIsmall: carbamoyl-phosphate synthase, small subunit IPR006274 Carbamoyl-phosphate synthase, small subunit 8 374 2.4E-142
Gene3D G3DSA:3.40.50.880 IPR029062 Class I glutamine amidotransferase-like 154 376 1.4E-72
ProSiteProfiles PS51273 Glutamine amidotransferase type 1 domain profile. IPR017926 Glutamine amidotransferase 192 379 27.61
Pfam PF00117 Glutamine amidotransferase class-I IPR017926 Glutamine amidotransferase 196 370 2.2E-45
PRINTS PR00096 Glutamine amidotransferase superfamily signature 348 361 6.2E-10
Pfam PF00988 Carbamoyl-phosphate synthase small chain, CPSase domain IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain 8 135 7.5E-52
PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 305 316 6.5E-39
CDD cd01744 GATase1_CPSase IPR035686 Carbamoyl-phosphate synthase small subunit, GATase1 domain 193 369 5.50379E-113
SUPERFAMILY SSF52021 IPR036480 Carbamoyl-phosphate synthase small subunit, N-terminal domain superfamily 7 152 2.22E-57
PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 193 207 6.5E-39
PRINTS PR00096 Glutamine amidotransferase superfamily signature 263 274 6.2E-10
PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 232 246 6.5E-39
SUPERFAMILY SSF52317 IPR029062 Class I glutamine amidotransferase-like 158 374 1.07E-61
Hamap MF_01209 Carbamoyl-phosphate synthase small chain [carA]. IPR006274 Carbamoyl-phosphate synthase, small subunit 6 377 48.011
PRINTS PR00096 Glutamine amidotransferase superfamily signature 235 244 6.2E-10
PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 263 279 6.5E-39
PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 280 297 6.5E-39
Gene3D G3DSA:3.50.30.20 IPR036480 Carbamoyl-phosphate synthase small subunit, N-terminal domain superfamily 6 153 1.3E-57
SMART SM01097 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain 6 136 7.7E-90

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.