Burkholderia pseudomallei K96243, BPSL0212 (metK)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0004478 methionine adenosyltransferase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00438
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0005524 ATP binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01034
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006556 S-adenosylmethionine biosynthetic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00438
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Pathways

Database Xref Pathway Version Evidence PMID
KEGG (InterPro) 00270 Cysteine and methionine metabolism InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG bps01100 Metabolic pathways 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG bps00270 Cysteine and methionine metabolism 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG bps01230 Biosynthesis of amino acids 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
MetaCyc <i>S</i>-adenosyl-L-methionine cycle II InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG bps01110 Biosynthesis of secondary metabolites 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
MetaCyc 2'-deoxymugineic acid phytosiderophore biosynthesis InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
ProSitePatterns PS00376 S-adenosylmethionine synthase signature 1. IPR022631 S-adenosylmethionine synthetase, conserved site 119 129 -
TIGRFAM TIGR01034 metK: methionine adenosyltransferase IPR002133 S-adenosylmethionine synthetase 6 383 1.1E-182
Gene3D G3DSA:3.30.300.10 6 236 1.3E-177
Gene3D G3DSA:3.30.300.10 103 377 1.3E-177
SUPERFAMILY SSF55973 IPR022636 S-adenosylmethionine synthetase superfamily 236 385 3.02E-68
PIRSF PIRSF000497 IPR002133 S-adenosylmethionine synthetase 1 387 4.8E-173
ProSitePatterns PS00377 S-adenosylmethionine synthase signature 2. IPR022631 S-adenosylmethionine synthetase, conserved site 262 270 -
Hamap MF_00086 S-adenosylmethionine synthase [metK]. IPR002133 S-adenosylmethionine synthetase 3 386 56.626
Pfam PF02772 S-adenosylmethionine synthetase, central domain IPR022629 S-adenosylmethionine synthetase, central domain 117 234 3.0E-46
SUPERFAMILY SSF55973 IPR022636 S-adenosylmethionine synthetase superfamily 113 235 8.24E-52
CDD cd18079 S-AdoMet_synt 6 377 0.0
SUPERFAMILY SSF55973 IPR022636 S-adenosylmethionine synthetase superfamily 4 110 1.77E-45
Pfam PF00438 S-adenosylmethionine synthetase, N-terminal domain IPR022628 S-adenosylmethionine synthetase, N-terminal 5 102 1.9E-40
Pfam PF02773 S-adenosylmethionine synthetase, C-terminal domain IPR022630 S-adenosylmethionine synthetase, C-terminal 236 374 5.9E-68
Gene3D G3DSA:3.30.300.10 12 273 1.3E-177

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.