Burkholderia cenocepacia AU 1054, BCEN_RS12635
Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
Gene Ontology
| Ontology | Accession | Term | GO Evidence | Evidence Ontology (ECO) Code | Reference | Comments |
|---|---|---|---|---|---|---|
| Molecular Function | GO:0004357 | glutamate-cysteine ligase activity |
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01434
|
ECO:0000259 match to InterPro signature evidence used in automatic assertion |
||
| Molecular Function | GO:0003824 | catalytic activity |
Inferred from Sequence Model
Term mapped from: InterPro:SSF55931
|
ECO:0000259 match to InterPro signature evidence used in automatic assertion |
||
| Biological Process | GO:0006750 | glutathione biosynthetic process |
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01434
|
ECO:0000259 match to InterPro signature evidence used in automatic assertion |
Pathways
| Database | Xref | Pathway | Version | Evidence | PMID |
|---|---|---|---|---|---|
| MetaCyc | ophthalmate biosynthesis | InterPro 5.36-75.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
||
| KEGG (InterPro) | 00480 | Glutathione metabolism | InterPro 5.36-75.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
|
| MetaCyc | ergothioneine biosynthesis I (bacteria) | InterPro 5.36-75.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
||
| KEGG (InterPro) | 00270 | Cysteine and methionine metabolism | InterPro 5.36-75.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
|
| MetaCyc | homoglutathione biosynthesis | InterPro 5.36-75.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
Functional Predictions from Interpro
| Analysis | Accession | Description | Interpro Accession | Interpro Description | Amino Acid Start | Amino Acid Stop | E-value |
|---|---|---|---|---|---|---|---|
| Pfam | PF04262 | Glutamate-cysteine ligase | IPR007370 | Glutamate--cysteine ligase | 18 | 389 | 4.8E-161 |
| Gene3D | G3DSA:3.30.590.20 | 28 | 533 | 5.3E-186 | |||
| TIGRFAM | TIGR01434 | glu_cys_ligase: glutamate--cysteine ligase | IPR006334 | Glutamate--cysteine ligase, monofunctional | 27 | 527 | 2.9E-189 |
| SUPERFAMILY | SSF55931 | IPR014746 | Glutamine synthetase/guanido kinase, catalytic domain | 18 | 524 | 3.14E-187 | |
| Hamap | MF_00578 | Glutamate--cysteine ligase [gshA]. | IPR006334 | Glutamate--cysteine ligase, monofunctional | 1 | 537 | 223.546 |
Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.