Burkholderia cenocepacia AU 1054, BCEN_RS12530

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0003677 DNA binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PR00417
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006265 DNA topological change
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PR00417
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003916 DNA topoisomerase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PR00417
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003917 DNA topoisomerase type I activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PS00396
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Gene3D G3DSA:1.10.460.10 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 160 604 5.3E-158
ProSitePatterns PS00396 Prokaryotic DNA topoisomerase I active site. IPR023406 DNA topoisomerase, type IA, active site 316 331 -
SMART SM00493 IPR006171 TOPRIM domain 3 126 2.5E-13
Gene3D G3DSA:2.70.20.10 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 215 487 5.3E-158
Pfam PF01131 DNA topoisomerase IPR013497 DNA topoisomerase, type IA, central 154 595 5.8E-114
SUPERFAMILY SSF56712 IPR023405 DNA topoisomerase, type IA, core domain 3 609 7.46E-173
ProSiteProfiles PS50880 Toprim domain profile. IPR006171 TOPRIM domain 3 136 17.894
Pfam PF13342 C-terminal repeat of topoisomerase IPR025589 Topoisomerase C-terminal repeat 645 709 5.4E-20
PRINTS PR00417 Prokaryotic DNA topoisomerase I signature IPR013497 DNA topoisomerase, type IA, central 100 113 3.8E-27
Gene3D G3DSA:3.40.50.140 3 153 2.2E-48
PRINTS PR00417 Prokaryotic DNA topoisomerase I signature IPR013497 DNA topoisomerase, type IA, central 322 331 3.8E-27
Pfam PF13342 C-terminal repeat of topoisomerase IPR025589 Topoisomerase C-terminal repeat 756 816 1.1E-17
MobiDBLite mobidb-lite consensus disorder prediction 819 865 -
Pfam PF01751 Toprim domain IPR006171 TOPRIM domain 5 132 1.0E-11
PRINTS PR00417 Prokaryotic DNA topoisomerase I signature IPR013497 DNA topoisomerase, type IA, central 191 209 3.8E-27
PRINTS PR00417 Prokaryotic DNA topoisomerase I signature IPR013497 DNA topoisomerase, type IA, central 404 420 3.8E-27
TIGRFAM TIGR01056 topB: DNA topoisomerase III IPR005738 DNA topoisomerase III 3 616 7.0E-168
CDD cd03362 TOPRIM_TopoIA_TopoIII IPR034144 DNA topoisomerase 3-like, TOPRIM domain 3 147 1.8995E-49
Gene3D G3DSA:1.10.290.10 IPR013826 DNA topoisomerase, type IA, central region, subdomain 3 288 418 5.3E-158
SMART SM00437 IPR003602 DNA topoisomerase, type IA, DNA-binding domain 279 556 2.7E-71
PRINTS PR00417 Prokaryotic DNA topoisomerase I signature IPR013497 DNA topoisomerase, type IA, central 519 533 3.8E-27
MobiDBLite mobidb-lite consensus disorder prediction 819 852 -
CDD cd00186 TOP1Ac IPR013497 DNA topoisomerase, type IA, central 155 605 4.30969E-112
SMART SM00436 IPR003601 DNA topoisomerase, type IA, domain 2 126 221 1.2E-23

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.