Burkholderia cenocepacia AU 1054, BCEN_RS11675
Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
Gene Ontology
| Ontology | Accession | Term | GO Evidence | Evidence Ontology (ECO) Code | Reference | Comments |
|---|---|---|---|---|---|---|
| Molecular Function | GO:0003824 | catalytic activity |
Inferred from Sequence Model
Term mapped from: InterPro:G3DSA:3.20.20.70
|
ECO:0000259 match to InterPro signature evidence used in automatic assertion |
||
| Molecular Function | GO:0004419 | hydroxymethylglutaryl-CoA lyase activity |
Inferred from Sequence Model
Term mapped from: InterPro:PS01062
|
ECO:0000259 match to InterPro signature evidence used in automatic assertion |
Pathways
| Database | Xref | Pathway | Version | Evidence | PMID |
|---|---|---|---|---|---|
| KEGG (InterPro) | 00650 | Butanoate metabolism | InterPro 5.36-75.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
|
| MetaCyc | mevalonate degradation | InterPro 5.36-75.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
||
| KEGG (InterPro) | 00072 | Synthesis and degradation of ketone bodies | InterPro 5.36-75.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
|
| KEGG (InterPro) | 00281 | Geraniol degradation | InterPro 5.36-75.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
|
| KEGG (InterPro) | 00280 | Valine, leucine and isoleucine degradation | InterPro 5.36-75.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
Functional Predictions from Interpro
| Analysis | Accession | Description | Interpro Accession | Interpro Description | Amino Acid Start | Amino Acid Stop | E-value |
|---|---|---|---|---|---|---|---|
| Gene3D | G3DSA:3.20.20.70 | IPR013785 | Aldolase-type TIM barrel | 1 | 300 | 3.5E-133 | |
| ProSiteProfiles | PS50991 | Pyruvate carboxyltransferase domain. | IPR000891 | Pyruvate carboxyltransferase | 7 | 274 | 35.967 |
| CDD | cd07938 | DRE_TIM_HMGL | 9 | 281 | 3.49996E-167 | ||
| SUPERFAMILY | SSF51569 | 1 | 291 | 1.22E-73 | |||
| ProSitePatterns | PS01062 | Hydroxymethylglutaryl-coenzyme A lyase active site. | IPR000138 | Hydroxymethylglutaryl-CoA lyase, active site | 233 | 242 | - |
| Pfam | PF00682 | HMGL-like | IPR000891 | Pyruvate carboxyltransferase | 7 | 280 | 5.1E-56 |
Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.