Burkholderia cenocepacia AU 1054, BCEN_RS03680
Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
Gene Ontology
| Ontology | Accession | Term | GO Evidence | Evidence Ontology (ECO) Code | Reference | Comments |
|---|---|---|---|---|---|---|
| Molecular Function | GO:0016830 | carbon-carbon lyase activity |
Inferred from Sequence Model
Term mapped from: InterPro:MF_00089
|
ECO:0000259 match to InterPro signature evidence used in automatic assertion |
||
| Biological Process | GO:0009228 | thiamine biosynthetic process |
Inferred from Sequence Model
Term mapped from: InterPro:PF01964
|
ECO:0000259 match to InterPro signature evidence used in automatic assertion |
||
| Molecular Function | GO:0051536 | iron-sulfur cluster binding |
Inferred from Sequence Model
Term mapped from: InterPro:PF01964
|
ECO:0000259 match to InterPro signature evidence used in automatic assertion |
Pathways
| Database | Xref | Pathway | Version | Evidence | PMID |
|---|---|---|---|---|---|
| KEGG (InterPro) | 00730 | Thiamine metabolism | InterPro 5.36-75.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
|
| MetaCyc | 4-amino-2-methyl-5-diphosphomethylpyrimidine biosynthesis | InterPro 5.36-75.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
Functional Predictions from Interpro
| Analysis | Accession | Description | Interpro Accession | Interpro Description | Amino Acid Start | Amino Acid Stop | E-value |
|---|---|---|---|---|---|---|---|
| Pfam | PF13667 | ThiC-associated domain | IPR025747 | ThiC-associated domain | 21 | 98 | 2.1E-34 |
| SFLD | SFLDS00113 | Radical SAM Phosphomethylpyrimidine Synthase | 11 | 642 | 0.0 | ||
| SFLD | SFLDG01114 | phosphomethylpyrimidine synthase (ThiC) | 17 | 641 | 0.0 | ||
| Hamap | MF_00089 | Phosphomethylpyrimidine synthase [thiC]. | IPR037509 | Phosphomethylpyrimidine synthase | 138 | 609 | 100.04 |
| SFLD | SFLDF00407 | phosphomethylpyrimidine synthase (ThiC) | IPR002817 | Phosphomethylpyrimidine synthase ThiC/5-hydroxybenzimidazole synthase BzaA/B | 139 | 604 | 0.0 |
| Pfam | PF01964 | Radical SAM ThiC family | IPR002817 | Phosphomethylpyrimidine synthase ThiC/5-hydroxybenzimidazole synthase BzaA/B | 139 | 604 | 2.8E-200 |
| Gene3D | G3DSA:3.20.20.540 | IPR038521 | ThiC/Bza superfamily | 227 | 540 | 3.3E-153 | |
| TIGRFAM | TIGR00190 | thiC: phosphomethylpyrimidine synthase | IPR002817 | Phosphomethylpyrimidine synthase ThiC/5-hydroxybenzimidazole synthase BzaA/B | 138 | 607 | 1.3E-216 |
Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.