Strain |
Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest |
Locus Tag |
BPSS1439
|
Name |
bbfA
|
Replicon | chromosome 2 |
Genomic location | 1960277 - 1964869 (+ strand) |
RefSeq | YP_111449.1 |
GI | |
Entrez | 3095852 |
INSDC | CAH38912.1 |
NCBI Locus Tag | BPSS1439 |
RefSeq | YP_111449.1,GeneID |
UniParc | UPI000043BCC5 |
UniProtKB Acc | Q63KC3 |
UniProtKB ID | Q63KC3_BURPS |
UniRef100 | UniRef100_Q63KC3 |
UniRef50 | UniRef50_Q3JLD1 |
UniRef90 | UniRef90_Q63KC3 |
Feature Type | CDS |
Coding Frame | 1 |
Product Name |
BbfA
|
Synonyms |
membrane-anchored cell surface protein |
Evidence for Translation | |
Charge (pH 7) | 1.37 |
Kyte-Doolittle Hydrophobicity Value | 0.123 |
Molecular Weight (kDa) | 145459.4 |
Isoelectric Point (pI) | 8.04 |
Individual Mappings | |
Additional evidence for subcellular localization |
Source 1 | |
Database | BGD |
Category | Trimeric autotransporter |
Evidence |
ECO:0000315
mutant phenotype evidence used in manual assertion
|
Host Organism | Mus musculus |
Notes | BbfA mutation attenuated for virulence in BALB/c mouse model of melioidosis. |
Reference | 25830295 |
Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 74 genera
|
Burkholderia Ortholog Group |
BG020907 (7 members) |
Putative Inparalogs | None Found |
STRING database | Search for predicted protein-protein interactions using:
Search term: BPSS1439
Search term: bbfA
Search term: BbfA
|
Systematic mutagenesis of genes encoding predicted autotransported proteins of Burkholderia pseudomallei identifies factors mediating virulence in mice, net intracellular replication and a novel protein conferring serum resistance.
Lazar Adler NR, Stevens MP, Dean RE, Saint RJ, Pankhania D, Prior JL, Atkins TP, Kessler B, Nithichanon A, Lertmemongkolchai G, Galyov EE
PLoS One 2015;10(4):e0121271
PubMed ID: 25830295
|
Identification of a predicted trimeric autotransporter adhesin required for biofilm formation of Burkholderia pseudomallei.
Lazar Adler NR, Dean RE, Saint RJ, Stevens MP, Prior JL, Atkins TP, Galyov EE
PLoS One 2013;8(11):e79461
PubMed ID: 24223950
|