Burkholderia cenocepacia J2315, BCAM2632

Gene Feature Overview

Strain	Burkholderia cenocepacia J2315 GCF_000009485.1|latest
Locus Tag	BCAM2632
NCBI Locus Tag	QU43_RS67615
Name
Replicon	chromosome 2
Genomic location	2981288 - 2983417 (- strand)

Cross-References

RefSeq	WP_006491648.1
GI	206564470
Entrez	6930152
GI	206564470
INSDC	CAR56496.1
NCBI Locus Tag	QU43_RS67615
NCBI Old Locus Tag	BCAM2632
RefSeq	WP_006491648.1,GeneID
UniParc	UPI00017BA2AC
UniProtKB Acc	B4EKB7
UniProtKB ID	B4EKB7_BURCJ
UniRef100	UniRef100_A0A0D1DEU2
UniRef50	UniRef50_A9ALQ9
UniRef90	UniRef90_B1Z1R1

Product

Feature Type	CDS
Coding Frame	1
Product Name	putative penicillin-binding protein Product Name Confidence: Class 1
Synonyms	Class A penicillin-binding protein
Evidence for Translation
Charge (pH 7)	10.58
Kyte-Doolittle Hydrophobicity Value	-0.171
Molecular Weight (kDa)	76638.4
Isoelectric Point (pI)	9.35

Subcellular localization

Individual Mappings	Localization Confidence PMID Cytoplasmic Membrane Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 556 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group	BG004249 (594 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: BCAM2632 Search term: putative penicillin-binding protein

Human Homologs

References

Expression and characterization of penicillin-binding proteins in Burkholderia cenocepacia. Specht KM, Sheetz KH, Alexander CM, Lamech LT, O'Connor LH, Walker DM, Stevenson HP Curr Microbiol 2010 Apr;60(4):274-9 PubMed ID: 19924480