Burkholderia cenocepacia J2315, BCAM2230 (pchE)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Burkholderia cenocepacia J2315
GCF_000009485.1|latest
Locus Tag
BCAM2230
NCBI Locus TagQU43_RS65515
Name
pchE
Replicon chromosome 2
Genomic location 2496696 - 2501069 (- strand)

Cross-References

RefSeq WP_012493508.1
GI 206564065
Entrez 6930591
GI 206564065
INSDC CAR56087.1
NCBI Locus Tag QU43_RS65515
NCBI Old Locus Tag BCAM2230
RefSeq WP_012493508.1,GeneID
UniParc UPI00017BA01E
UniProtKB Acc B4EGG1
UniProtKB ID B4EGG1_BURCJ
UniRef100 UniRef100_B4EGG1
UniRef50 UniRef50_Q2T477
UniRef90 UniRef90_B4EGG1

Product

Feature Type CDS
Coding Frame 1
Product Name
dihydroaeruginoic acid synthetase PchE
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Charge (pH 7) -35.47
Kyte-Doolittle Hydrophobicity Value 0.099
Molecular Weight (kDa) 155264.4
Isoelectric Point (pI) 5.30

Subcellular localization

Individual Mappings
Localization Confidence PMID
Unknown (This protein may have multiple localization sites) Class 3
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 556 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG006694 (403 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BCAM2230
Search term: pchE

Human Homologs

Ensembl 97, assembly GRCh38.p12
aminoadipate-semialdehyde dehydrogenase [Source:HGNC Symbol;Acc:HGNC:23993]
E-value: 4.1e-18
Percent Identity: 28.8

Human Homologs

Ensembl 97, assembly GRCh38.p12
aminoadipate-semialdehyde dehydrogenase [Source:HGNC Symbol;Acc:HGNC:23993]
E-value: 4.1e-18
Percent Identity: 28.8

Human Homologs

Ensembl 97, assembly GRCh38.p12
aminoadipate-semialdehyde dehydrogenase [Source:HGNC Symbol;Acc:HGNC:23993]
E-value: 4.1e-18
Percent Identity: 28.8

Human Homologs

Ensembl 97, assembly GRCh38.p12
aminoadipate-semialdehyde dehydrogenase [Source:HGNC Symbol;Acc:HGNC:23993]
E-value: 4.1e-18
Percent Identity: 28.8

Human Homologs

Ensembl 97, assembly GRCh38.p12
aminoadipate-semialdehyde dehydrogenase [Source:HGNC Symbol;Acc:HGNC:23993]
E-value: 4.1e-18
Percent Identity: 28.8

References

Dihydroaeruginoic acid synthetase and pyochelin synthetase, products of the pchEF genes, are induced by extracellular pyochelin in Pseudomonas aeruginosa.
Reimmann C, Serino L, Beyeler M, Haas D
Microbiology 1998 Nov;144 ( Pt 11):3135-48
PubMed ID: 9846750
Erratum in: J Bacteriol. 2009 Apr;191(8):2907.
The genome of Burkholderia cenocepacia J2315, an epidemic pathogen of cystic fibrosis patients.
J Bacteriol. 2009 Jan;191(1):261-77.
PubMed ID: 18931103