Burkholderia cenocepacia J2315, BCAM0328 (virB6)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia cenocepacia J2315
GCF_000009485.1|latest
Locus Tag
BCAM0328
NCBI Locus TagQU43_RS56050
Name
virB6
Synonym: bcvirB6
Replicon chromosome 2
Genomic location 383495 - 384646 (+ strand)
CommentThis gene is part of the B. cenocepacia J2315 VirB-VirD-like type IV secretion system cluster.

Cross-References

RefSeq WP_006493306.1
GI 206562194
Entrez 6928117
GI 206562194
INSDC CAR54187.1
NCBI Locus Tag QU43_RS56050
NCBI Old Locus Tag BCAM0328
RefSeq WP_006493306.1,GeneID
UniParc UPI00017B9B2C
UniProtKB Acc B4EIR9
UniProtKB ID B4EIR9_BURCJ
UniRef100 UniRef100_A0A0D1DMM5
UniRef50 UniRef50_Q140D4
UniRef90 UniRef90_A0AXD1

Product

Feature Type CDS
Coding Frame 1
Product Name
putative type IV secretion system protein VirB6
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Charge (pH 7) 0.07
Kyte-Doolittle Hydrophobicity Value 0.625
Molecular Weight (kDa) 39233.9
Isoelectric Point (pI) 7.03

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 36 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG006327 (74 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BCAM0328
Search term: virB6

References

Involvement of a plasmid-encoded type IV secretion system in the plant tissue watersoaking phenotype of Burkholderia cenocepacia.
Engledow AS, Medrano EG, Mahenthiralingam E, LiPuma JJ, Gonzalez CF.
J Bacteriol. 2004 Sep;186(18):6015-24.
PubMed ID: 15342570
Two type IV secretion systems with different functions in Burkholderia cenocepacia K56-2.
Zhang R, LiPuma JJ, Gonzalez CF.
Microbiology. 2009 Dec;155(Pt 12):4005-13.
PubMed ID: 19744991
A type IV secretion system contributes to intracellular survival and replication of Burkholderia cenocepacia.
Sajjan SU, Carmody LA, Gonzalez CF, LiPuma JJ.
Infect Immun. 2008 Dec;76(12):5447-55.
PubMed ID: 18824538