Burkholderia cenocepacia J2315, BCAM0327 (virB4)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia cenocepacia J2315
GCF_000009485.1|latest
Locus Tag
BCAM0327
NCBI Locus TagQU43_RS56045
Name
virB4
Synonym: bcvirB4
Replicon chromosome 2
Genomic location 381018 - 383498 (+ strand)
CommentThis gene is part of the B. cenocepacia J2315 VirB-VirD-like type IV secretion system cluster.

Cross-References

RefSeq WP_012493066.1
GI 206562193
Entrez 6928116
GI 206562193
INSDC CAR54186.1
NCBI Locus Tag QU43_RS56045
NCBI Old Locus Tag BCAM0327
RefSeq WP_012493066.1,GeneID
UniParc UPI00017B9B2B
UniProtKB Acc B4EIR8
UniProtKB ID B4EIR8_BURCJ
UniRef100 UniRef100_A0A0D1C9X4
UniRef50 UniRef50_A0A095G0C0
UniRef90 UniRef90_A0A095FBI1

Product

Feature Type CDS
Coding Frame 1
Product Name
putative type IV secretion system protein VirB4
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Charge (pH 7) -0.93
Kyte-Doolittle Hydrophobicity Value -0.261
Molecular Weight (kDa) 92845.7
Isoelectric Point (pI) 6.91

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 136 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG001868 (63 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BCAM0327
Search term: virB4

References

Involvement of a plasmid-encoded type IV secretion system in the plant tissue watersoaking phenotype of Burkholderia cenocepacia.
Engledow AS, Medrano EG, Mahenthiralingam E, LiPuma JJ, Gonzalez CF
J Bacteriol 2004 Sep;186(18):6015-24
PubMed ID: 15342570
Two type IV secretion systems with different functions in Burkholderia cenocepacia K56-2.
Zhang R, LiPuma JJ, Gonzalez CF
Microbiology 2009 Dec;155(Pt 12):4005-4013
PubMed ID: 19744991
A type IV secretion system contributes to intracellular survival and replication of Burkholderia cenocepacia.
Sajjan SU, Carmody LA, Gonzalez CF, LiPuma JJ
Infect Immun 2008 Dec;76(12):5447-55
PubMed ID: 18824538