Strain |
Burkholderia cenocepacia J2315
GCF_000009485.1|latest |
Locus Tag |
BCAL3119
|
NCBI Locus Tag | QU43_RS52325 |
Name |
wbiI
|
Replicon | chromosome 1 |
Genomic location | 3409126 - 3411009 (- strand) |
Comment | Belongs to the O antigen biosynthesis gene cluster |
RefSeq | WP_006485114.1 |
GI | 206561465 |
Entrez | 6934257 |
GI | 206561465 |
INSDC | CAR53443.1 |
NCBI Locus Tag | QU43_RS52325 |
NCBI Old Locus Tag | BCAL3119 |
RefSeq | WP_006485114.1,GeneID |
UniParc | UPI00017B9956 |
UniProtKB Acc | B4ECE0 |
UniProtKB ID | B4ECE0_BURCJ |
UniRef100 | UniRef100_B4ECE0 |
UniRef50 | UniRef50_G2J9Y1 |
UniRef90 | UniRef90_B4ECE0 |
Feature Type | CDS |
Coding Frame | 1 |
Product Name |
nucleotide sugar epimerase/dehydratase
|
Synonyms |
WbiI |
Evidence for Translation | |
Charge (pH 7) | 6.50 |
Kyte-Doolittle Hydrophobicity Value | 0.171 |
Molecular Weight (kDa) | 69230.0 |
Isoelectric Point (pI) | 8.54 |
Individual Mappings | |
Additional evidence for subcellular localization |
Source 1 | |
Database | BGD |
Category | Siderophore biosynthesis and uptake (ornibactin) |
Evidence |
ECO:0000315
mutant phenotype evidence used in manual assertion
|
Host Organism | Rattus norvegicus |
Notes | wbiI mutant attenuated for virulence in agar bead model of chronic lung infection |
Reference | 15213146 |
Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 464 genera
|
Burkholderia Ortholog Group |
BG000742 (649 members) |
Putative Inparalogs | None Found |
STRING database | Search for predicted protein-protein interactions using:
Search term: BCAL3119
Search term: wbiI
Search term: nucleotide sugar epimerase/dehydratase
|
Correlation of wbiI genotype, serotype, and isolate source within species of the Burkholderia cepacia complex.
Vinion-Dubiel AD, Spilker T, Dean CR, Monteil H, LiPuma JJ, Goldberg JB
J Clin Microbiol 2004 Sep;42(9):4121-6
PubMed ID: 15364998
|
Reconstitution of O-specific lipopolysaccharide expression in Burkholderia cenocepacia strain J2315, which is associated with transmissible infections in patients with cystic fibrosis.
Ortega X, Hunt TA, Loutet S, Vinion-Dubiel AD, Datta A, Choudhury B, Goldberg JB, Carlson R, Valvano MA
J Bacteriol 2005 Feb;187(4):1324-33
PubMed ID: 15687196
|